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Table 1 Clinicopathological characteristics and baseline of all cases, training set and test set

From: Application of preoperative ultrasound features combined with clinical factors in predicting HER2-positive subtype (non-luminal) breast cancer

Characteristics

All cases

(N = 1670)

Training set

(N = 1169)

Test set

(N = 501)

P value

Age (year)

53.1 [45, 61]

53 [45,61]

53 [46,61]

0.604

tumor size (mm)

21.0 [15, 26]

20.0 [15, 26]

20.0 [15, 26]

0.393

BMI value

23.3 [21.4, 25.4]

23.3 [21.5, 25.4]

23.23 [21.2, 25.1]

0.335

Menopause

   

0.724

 No

769 (46.0)

535 (45.8)

234 (46.7)

 

 Yes

901 (54.0)

634 (54.2)

267 (53.3)

 

Breast cancer family history

   

0.566

 No

1610 (96.4)

1125 (96.2)

485 (96.8)

 

 Yes

60 (3.6)

44 (3.8)

16 (3.2)

 

Palpable ALN

   

0.534

 No

1348 (80.7)

939 (80.3)

409 (81.6)

 

 Yes

322 (19.3)

230 (19.7)

92 (18.4)

 

US ALN

    

 No

1031 (61.7)

712 (60.9)

319 (63.7)

0.287

 Yes

639 (38.3)

457 (39.1)

182 (36.3)

 

Shape

    

 Oval

90 (5.4)

67 (5.7)

23 (4.6)

0.259

 Round

62 (3.7)

48 (4.1)

14 (2.8)

 

 Irregular

1518 (90.9)

1054 (90.2)

464 (92.6)

 

Orientation

   

0.860

 Parallel

1048 (62.8)

732 (62.6)

316 (63.1)

 

 Not parallel

622 (37.2)

437 (37.4)

185 (36.9)

 

Margin

   

0.690

 Circumscribed

37 (2.2)

27 (2.3)

10 (2.0)

 

 Not circumscribed

1633 (97.8)

1142 (97.7)

491 (98.0)

 

Boundary

   

0.168

 Abrupt

1068 (64.0)

760 (65.0)

308 (61.5)

 

 Halo

602 (36.0)

409 (35.0)

193 (38.5)

 

Echo pattern

   

0.945

 Hypoechoic

1483 (88.8)

1041 (89.1)

442 (88.2)

 

 Isoechoic

57 (3.4)

40 (3.4)

17 (3.4)

 

 Complex

103 (6.2)

70 (6.0)

33 (6.6)

 

 Hyperechoic

27 (1.6)

18 (1.5)

9 (1.8)

 

Posterior acoustic features

   

0.379

 No

504 (30.2)

350 (30.0)

154 (30.7)

 

 Enhancement

560 (33.5)

393 (33.6)

167 (33.4)

 

 Shadowing

539 (32.3)

385 (32.9)

154 (30.7)

 

 Combined

67 (4.0)

41 (3.5)

26 (5.2)

 

Calcifications

   

0.010

 No

826 (49.5)

554 (47.4)

272 (54.3)

 

 Yes

844 (50.5)

615 (52.6)

229 (45.7)

 

Vascular degree

   

0.973

 0

226 (13.5)

160 (13.7)

66 (13.2)

 

 I

275 (16.5)

190 (16.2)

85 (17.0)

 

 II

766 (45.9)

535 (45.8)

231 (46.1)

 

 III

403 (24.1)

284 (24.3)

119 (23.7)

 
  1. BMI body mass index, ALN axillary lymph node, US ultrasound
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