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Table 1 Advantages and disadvantages of multi-modality  imaging in pericardial disease evaluation [3,4,5]

From: Multiple pericardial hematomas: a case report and mini-review in multimodality imaging

Modalities

Advantages

Disadvantages

Echocardiography

Easily performed (bedside and in emergency setting)

Identification of:

  Pericardial effusion

  Intrapericardial clot

Hemodynamic assessment for:

  Tamponade

  Constrictive physiology

Limitation for window:

  Narrow field of view

  Poor window in obesity, Chronic obstructive pulmonary disease (COPD), or patient with mechanical ventilation

Limited in the assessment of:

  Pericardial thickness

  Tissue characterization

CT Scan

Identification of:

  Pericardial thickening

  Pericardial effusion

  Pericardial mass (cysts, thrombus/hematoma)

 Pericardial calcification

Evaluation of associated intrathoracic abnormalities, such as:

  Pleural abnormalities (thickening, effusion)

  Pulmonary abnormalities (masses or other lesions)

  Lymph node involvement

Risks associated with radiation and contrast

Unsuitable in critically-ill or uncooperative patients

Limitation in:

  Evaluation of the elasticity of the pericardium

  Hemodynamic assessment, especially in assessing constrictive and tamponade physiology

  Differentiation of hemorrhagic effusions with thrombus/ hematoma (similar Hounsfield unit attenuation)

CMRI

A more detailed evaluation of pericardial anatomy

Assessment of pericardial thickness

Identification and characterizations of

  Pericardial fluid

  Pericardial masses

High cost, time-consuming

Unsuitable in critically-ill or uncooperative patients

Limited use in:

  Metal prosthetic; ICD or pacemaker-implanted patient

  End-stage renal disease: related to contrast

Poor-quality for calcification evaluation

Nuclear imaging

Hybrid: Anatomic and metabolic evaluation

Identification and detection of:

  Neoplasm: FDG/PET

  Infection/Inflammation

High cost, high maintenance

Risk of radiation

No data on pericardial hematoma and cyst