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Table 2 Comparison of sensitivity, specificity, and accuracy in the detection of PHPT via three methods (%)

From: Efficacy of ultrasonography and Tc-99m MIBI SPECT/CT in preoperative localization of parathyroid adenomas causing primary hyperthyroidism

 

Sensitivity

Specificity

Accuracy

US

93.0 (93/100)

25.0 (2/8)

88.0 (95/108)

Tc-99m MIBI SPECT/CT

63.0 (63/100)a

62.5 (5/8)

63.0 (68/108)a

US + Tc-99m MIBI SPECT/CT

96.0 (96/100)bc

12.5 (1/8)

97.0 (97/108)bc

χ2

49.554

4.875

30.648

P

< 0.001

0.087

< 0.001

  1. There were significant differences in sensitivity (χ2 = 49.554, P < 0.001) and accuracy (χ2 = 30.648, P < 0.001) among the three groups, and pairwise comparison was performed for row x column segmentation
  2. aCompared with US, the differences of sensitivity (χ2 = 26.224, P < 0.001) and accuracy (χ2 = 18.227, P < 0.001) were statistically significant
  3. bCompared with Tc-99m MIBI SPECT/CT, the differences were statistically significant (χ2 = 33.410, P < 0.001 for sensitivity; χ2 = 21.587, P < 0.001 for accuracy)
  4. cCompared with US, there were no significant differences (P = 0.352 and P = 0.665, respectively). There were no statistically significant differences in specificity between the three methods (χ2 = 4.875, P = 0.087)