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Table 4 Receiver operating characteristic analyses of clinical characteristics and dual-energy spectral computed tomography quantitative parameters in necrotic lung cancer and pulmonary mass-like inflammatory lesions

From: Differentiating malignant and benign necrotic lung lesions using kVp-switching dual-energy spectral computed tomography

Characteristics

AUC (95% CI)

Optimal cut-off value

Sensitivity

Specificity

Age (years)

0.747 (0.626–0.868)

59

0.750

0.742

Elevation of C-reactive protein concentration

0.691 (0.566–0.815)

–

0.806

0.575

Quantitative parameters of necrosis

    

 K40–65 keV in NCS

0.841 (0.749–0.933)

 − 0.12

0.900

0.742

 K40–65 keV in AP

0.641 (0.510–0.771)

0.22

0.650

0.645

 K40–65 keV in VP

0.660 (0.531–0.790)

0.11

0.875

0.452

 Effective atomic number in NCS

0.828 (0.731–0.926)

7.54

0.825

0.774

Quantitative parameters of solid portion

    

 IC in VP (mg/mL)

0.754 (0.638–0.870)

1.85

0.516

0.925

  1. AUC, area under the receiver operating characteristic curve; CI: confidence interval; K40–65 keV, the slope of the spectral curve from 40 to 65 keV; NCS, non-contrast-enhanced scanning; AP, arterial phase; VP, venous phase; IC, iodine concentration
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BMC Medical Imaging

ISSN: 1471-2342

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