Table 1 Clinical characteristics

Age

51 ± 12

57 ± 16

73 ± 9*^,**

73 ± 14*^,**

0.004

Male, n (%)

33 (50)

19 (58)

9(25)

17 (38)

0.025

BMI (kg/m²)

29 ± 3

29 ± 4

30 ± 5

30 ± 7

NS

Diabetes Mellitus, n (%)

0 (0)

4 (12)*

14 (39)*^,**

11 (24)*

 < 0.001

Hypertension, n (%)

0 (0)

14 (42)*

23 (64)*

32 (71)*^,**

 < 0.001

Hyperlipidemia, n (%)

0 (0)

11 (33)*

15 (42)*

19 (42)*

 < 0.001

Smoking, n (%)

0 (0)

6 (18)*

5 (14)

3 (7)

 < 0.001

Renal Failure, n (%)

0 (0)

0 (0)

4 (11)*^,**

2 (4)

 < 0.001

Dyspnea, n (%)

0 (0)

1 (3)

8 (22)*

14 (31)*^,**

 < 0.001