Table 4 Diagnostic performance of different quantitative MRI parameters for and the assessment of liver fibrosis in patients without (< F2) and with significant (≥ F2) fibrosis
Variable | AUC | Cutoff value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) |
|---|---|---|---|---|---|---|---|
Hepatic native T1 (ms) | 0.711 |  > 562.7 | 52.6 (31.7–72.7) | 100.0 (77.2–100.0) | 100.0 (72.2–100.0) | 59.1 (38.7–76.7) | 71.9 (54.6–84.4) |
Hepatic extracellular volume fraction (%) | 0.858 |  > 27.2 | 84.2 (62.4–94.5) | 84.6 (57.8–95.7) | 88.9 (67.2–96.9) | 78.6 (52.4–92.4) | 84.4 (68.2–93.1) |
Hepatic T2 (ms) | 0.686 |  > 52.0 | 57.9 (36.3–76.9) | 92.3 (66.7–98.6) | 91.7 (64.6–98.5) | 60.0 (38.7–78.1) | 71.9 (54.6–84.4) |
APRI score | 0.787 |  > 0.41 | 64.7 (41.3–82.7) | 84.6 (57.8–95.7) | 84.6 (57.8–95.7) | 64.7 (41.3–82.7) | 73.3 (55.6–85.8) |
FIB-4 score | 0.588 |  > 1.2 | 35.3 (17.3–58.7) | 76.9 (49.7–91.8) | 66.7 (35.4–87.9) | 47.6 (28.3–67.6) | 53.3 (36.1–69.8) |
ALT/AST ratio (de-Ritis) | 0.570 |  ≤ 0.76 | 58.8 (36.6–78.4) | 69.2 (42.4–87.3) | 71.4 (45.4–88.3) | 56.3 (33.2–76.9) | 63.3 (45.5–78.1) |
MELD score | 0.680 |  > 6 | 52.6 (31.7–72.7) | 84.6 (57.8–95.7) | 83.3 (55.2–95.3) | 55.0 (34.2–74.2) | 65.6 (48.3–79.6) |