Table 1 Clinical characteristics of patients without significant fibrosis (< F2) and with significant fibrosis (≥ F2)

Age (years)

43.1 ± 12.8

39.5 ± 17.5

Body mass index (kg/m²)

23.8 ± 2.9

24.8 ± 3.8

Sex

Male

7 (53.8%)

4/19 (21.1%)

Female

6 (46.2%)

15 (78.9%)

Hematocrit level (%)

43 ± 4

42 ± 6

Bilirubin (mg/dl)

0.56 ± 0.25

1.19 ± 0.98

ALT (U/l)

52.1 ± 55.3

118.1 ± 92.9

AST (U/l)

33.4 ± 11.4

81.9 ± 46.6

GGT (U/l)

155.5 ± 116.7

240.3 ± 180.5

Platelets cells × 10⁹/l

291.2 ± 81.1

248.5 ± 130.7

C-reactive protein level (mg/l)

12.4 ± 22.8

2.1 ± 1.5

AP (U/l)

285.8 ± 181.6

140.8 ± 45.4

Creatinine (mg/dl)

0.79 ± 0.09

0.79 ± 0.14

Albumin (g/l)

45.9 ± 3.2

42.8 ± 5.3

International normalized ratio

1.08 ± 0.28

1.05 ± 0.12

ASL/ALT (de-Ritis)

0.85 ± 0.28

0.82 ± 0.33

FIB-4

0.85 ± 0.62

1.84 ± 2.86

MELD

6.69 ± 2.21

7.47 ± 2.46

APRI

0.31 ± 0.19

0.94 ± 1.10

Mayo score

 − 1.09 ± 0.54

0.03 ± 1.34