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Table 3 Diagnostic utility of the different imaging modalities (per-patient analysis—histopathology available)

From: Impact of 18F-FDG PET/CT, CT and EBUS/TBNA on preoperative mediastinal nodal staging of NSCLC

Imaging modality

Sensitivity (%)

95% CI

Specificity (%)

95% CI

PPV (%)

95% CI

NPV (%)

95% CI

Accuracy (%)

95% CI

18F-FDG PET/CT

83.3

62.62–95.26

60.6

42.14–77.09

60.6

49.28–70.89

83.3

66.23–92.73

70.2

56.60–81.57

CT scan

54.6

32.21–75.61

38.2

22.17–56.44

36.4

26.43–47.62

56.5

41.00–70.86

44.6

31.34–58.53

EBUS/TBNA

83.3

35.88–99.58

90.9

58.72–99.77

83.3

42.72–97.10

90.9

62.33–98.37

88.2

63.56–98.54

Mediastinoscopy

50

15.70–84.30

100

87.23–100.00

100

NA

87.1

77.15–93.10

88.6

73.26–96.80