A post-market, multi-vessel evaluation of the imaging of peripheral arteries for diagnostic purposeS comparing optical Coherence tomogrApy and iNtravascular ultrasound imaging (SCAN)

Table 3 Mean ranking of the image quality of layered structure, non-layered structure, calcification, stent structure, and artifacts as rated by three readers of matched images captured by OCT and IVUS systems

Reader	Layered Structure^a		Non-Layered Structure^b		Calcification^c		Stent Structure^d		Artifacts^e
Reader	IVUS	OCT	IVUS	OCT	IVUS	OCT	IVUS	OCT	IVUS	OCT
1	1.58	1.12	2.97	2.08	2.28	2.05	2.00	1.48	2.15	1.68
1	p = 0.002		p < 0.001		p < 0.001		p < 0.001		p < 0.001
ICC intrareader	0.82	0.91	0.89	0.91	0.77	0.83	0.82	0.93	0.85	0.81
2	1.42	1.04	2.55	1.54	2.15	1.60	1.81	1.14	1.73	1.51
2	p = 0.02		p < 0.001		p < 0.001		p < 0.001		p < 0.001
ICC intrareader	0.70	0.83	0.73	0.81	0.91	0.85	0.84	0.88	0.92	0.83
3	1.83	2.29	2.58	1.84	2.95	2.68	1.52	1.67	1.22	2.33
3	p = 0.005		p < 0.001		p = 0.19		p = 0.52		p < 0.001
ICC intrareader	0.84	0.75	0.89	0.77	0.92	0.87	0.83	0.86	0.92	0.81

Scoring: ^a Layered structure (1- clear differentiation of vessel wall layers, 2- differentiation of 3 wall layers, 3-differentiation of 2 wall layers, 4- no differentiation visible); ^b Non-layered structure (1- excellent histology-like image quality to 5- unacceptably poor image quality); ^c Calcification (1- excellent histology-like image quality to 5- unacceptably poor image quality); ^d Stent structure (1 excellent image, 2 – acceptable image, 3 – unacceptably poor image); and ^e Artifacts (1-none, 2- tolerable/not limiting, 3-is intense and limits image quality)

ISSN: 1471-2342