A post-market, multi-vessel evaluation of the imaging of peripheral arteries for diagnostic purposeS comparing optical Coherence tomogrApy and iNtravascular ultrasound imaging (SCAN)

Table 2 Mean ranking of the image quality of layered structure, non-layered structure, calcification, stent structure, and artifacts as rated by three readers of matched images captured by OCT and IVUS systems

Vessel Characteristic	Mean score for IVUS images	Mean score for OCT images	Student’s t-Test	Mann-Whitney-Wilcoxon test
Layered structure^a	1.61	1.49	p = 0.19	z = 0.82 p = 0.41
Non-layered structure^b	2.70	1.82	p < 0.001	z = 11.04 p < 0.001
Calcification^c	2.45	2.11	p = 0.001	z = 2.80 p = 0.005
Stent structure^d	1.79	1.43	p = 0.004	z = 2.67 p = 0.007
Artifacts^e	1.87	1.79	p = 0.07	z = − 1.52 p = 0.12

Scoring: ^a Layered structure (1- clear differentiation of vessel wall layers, 2- differentiation of 3 wall layers, 3-differentiation of 2 wall layers, 4- no differentiation visible); ^b Non-layered structure (1- excellent histology-like image quality to 5- unacceptably poor image quality); ^c Calcification (1- excellent histology-like image quality to 5- unacceptably poor image quality); ^d Stent structure (1 excellent image, 2 – acceptable image, 3 – unacceptably poor image); and ^e Artifacts (1-none, 2- tolerable/not limiting, 3-is intense and limits image quality)

ISSN: 1471-2342