Discriminative pattern of reduced cerebral blood flow in Parkinson’s disease and Parkinsonism-Plus syndrome: an ASL-MRI study

Table 3 ROC analysis of CBF for differentiation between the PD and PPS groups

Brain region	AUC	Cutoff point	Sensitivity (%)	Specificity (%)	95% CI		p-value
Brain region	AUC	Cutoff point	Sensitivity (%)	Specificity (%)	Upper bound	Lower bound	p-value
SMA.L	0.831	33.723	0.800	0.750	0.696	0.967	0.001
THA.R	0.759	50.195	0.750	0.812	0.597	0.922	0.008
CN. L	0.725	24.544	0.900	0.625	0.547	0.903	0.022
IFG_Tri.L	0.719	39.483	0.650	0.875	0.545	0.892	0.026
MFG.L	0.694	44.581	0.550	0.937	0.521	0.866	0.048

Abbreviations: ROC, receiver operating characteristic; PD, Parkinson’s disease; PPS, Parkinsonism-Plus syndrome; AUC, area under the curve; CI, confidence interval; SMA, supplementary motor area; THA, thalamus; CN, caudate nucleus; IFG_Tri, triangle inferior frontal gyrus; MFG, middle frontal gyrus; L (R), left (right) hemisphere

ISSN: 1471-2342