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Table 1 Demographic differences in the training and testing cohorts No, number; m, median; SD standard deviation

From: Noninvasive KRAS mutation estimation in colorectal cancer using a deep learning method based on CT imaging

Characteristics

Training cohort

p value

Testing cohort

p value

 

Wild-type group

Mutated group

 

Wild-type group

Mutated group

 

Gender (No [%])

  

0.3239

  

0.4753

Male

36(59.02)

38(67.86)

 

18(81.81)

13(72.22)

 

Female

25(40.98)

18(32.14)

 

4(18.18)

5(27.78)

 

Age (m ± SD)

59.80 ±11.05

60.33 ±9.84

0.7853

57.68 ±9.86

59.56 ±

0.5389

Tumor size, (cm ± SD)

3.49 ±1.21

3.05 ±1.18

0.0492*

3.55 ±1.29

4.8 ±1.74

0.0129*

Tumor location (No [%])

  

0.8668

  

0.0419*

Ascending colon

4(6.56)

5(8.93)

 

0(0.00)

4(22.22)

 

Transverse colon

3(4.92)

3(5.36)

 

1(4.55)

0(0)

 

Descending colon

4(6.56)

2(3.57)

 

4(18.18)

3(16.67)

 

Sigmoid colon

27(44.26)

25(44.64)

 

11(50.00)

4(22.22)

 

Rectum

15(24.60)

18(32.14)

 

6(27.27)

4(22.22)

 

Cecum

7(11.48)

4(7.14)

 

0(0.00)

3(16.67)

 

T category (No [%])

  

0.0928

  

0.2645

T1

1(1.64)

0(0.00)

 

0(0.00)

0(0.00)

 

T2

5(8.20)

2(3.57)

 

2(9.09)

0(0.00)

 

T3

41(67.21)

49(87.5)

 

17(77.27)

13(72.22)

 

T4

13(21.31)

5(8.93)

 

3(13.63)

5(27.78)

 

N category (No [%])

  

0.2361

  

0.3657

N0

19(31.15)

12(21.43)

 

1(4.55)

0(0)

 

N1, N2

42(68.85)

44(78.58)

 

21(95.45)

18(100)

 

M category (No [%])

  

0.6719

  

0.7814

M0

38(62.30)

37(66.07)

 

15(68.18)

13(72.22)

 

M1

23(37.70)

19(33.93)

 

7(31.82)

5(27.78)

 
  1. p value <0.05 indicates a significant difference in patients’characteristics between the primary cohort and testing cohort. , P< 0.05.