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Table 4 Performances of imaging in detecting bone metastases of prostate cancer patients with first biochemical recurrence (patient-base analysis)

From: Comparison of 18F-sodium fluoride PET/CT, 18F-fluorocholine PET/CT and diffusion-weighted MRI for the detection of bone metastases in recurrent prostate cancer: a cost-effectiveness analysis in France

 

Se

Sp

PPV

NPV

Accuracy

κ

NaF PET/CT

 On-site

71% (5/7)

92% (44/48)

56% (5/9)

96% (44/46)

89% (49/55)

0.96

 Central

86% (6/7)

94% (45/48)

67% (6/9)

98% (45/46)

93% (51/55)

 

FCH PET/CT

 On-site

43% (3/7)

100% (48/48)

100% (3/3)

92% (48/52)

93% (51/55)

0.86

 Central

57% (4/7)

98% (47/48)

80% (4/5)

94% (47/50)

93% (51/55)

 

DW-MRI

 On-site

57% (4/7)

83% (40/48)

33% (4/12)

93% (40/43)

80% (40/55)

0.59

 Central

43% (3/7)

94% (45/48)

60% (3/5)

90% (45/50)

87% (48/55)

 
  1. Se sensitivity, Sp specificity, PPV positive predictive value, NPV negative predictive value
  2. NaF18F-sodium fluoride, FCH18F-fluorocholine, DW-MRI diffusion-weighted whole-body magnetic resonance imaging
  3. Κ Cohen’s kappa coefficient