Reduced regional flow in the left ventricle after anterior acute myocardial infarction: a case control study using 4D flow MRI

Table 3 LV flow parameters in controls and anterior AMI patients

Flow Parameter	Region	Controls (n = 19)	Anterior AMI (n = 12)	P-value	Δ_MI	95% CI
Peak Systolic Flow (L/min)	Base	16.2 ± 5.4	8.4 ± 6.8	0.28	−2.1	[−5.8, 1.6]
	Mid-ventricle	8.5 ± 3.6	5.5 ± 3	0.01	−3.9	[− 6.4, − 1.4]
	Apex	2.2 ± 1	1.4 ± 1.4	0.02	−1.4	[−2.6, − 0.3]
Peak Diastolic Flow (L/min)	Base	18.6 ± 6.9	13.3 ± 4.7	0.71	1.1	[−4.6, 6.8]
	Mid-ventricle	12 ± 4.3	9.1 ± 4.3	0.35	−1.6	[−4.9, 1.7]
	Apex	3.1 ± 1.5	2 ± 1.1	0.004	−2.4	[−4.0, − 0.9]
Average KEi_EDV (μJ/mL)	Whole LV	11.3 ± 2.7	16.6 ± 11.9	0.79	− 0.9	[−8.0, 6.1]
Direct Flow %	Whole LV	58 ± 11	26 ± 21	4E-08	−41	[−52, −31]
Retained Inflow %	Whole LV	15 ± 6	24 ± 7	.0003	12	[7, 18]
Delayed Ejection Flow %	Whole LV	16 ± 6	18 ± 6	0.005	8	[3, 13]
Residual Volume %	Whole LV	7 ± 6	29 ± 12	6E-06	21	[14, 28]

Note—Reported values are median ± interquartile range (IQR). P-values were computed using multivariable linear regression models with age, sex, and heart rate as covariates. Bold text represents a significant P-value. Δ_MI is the expected difference in the LV flow parameter due to the anterior AMI. 95% CI is the 95% confidence interval for Δ_MI
KEi_EDV: Kinetic energy indexed to end diastolic volume

ISSN: 1471-2342