Potential use of a diluted high-relaxivity gadolinium-based intra-articular contrast agent for magnetic resonance arthrography: an in-vitro study

Table 2 Comparison of signal intensities of different Gd-BOPTA concentrations to Gd-DTPA 2 mmol/l with or without addition of synovial fluid

			Gd-BOPTA 0.5 mmol/l	Gd-BOPTA 0.67 mmol/l	Gd-BOPTA 1 mmol/l	Gd-BOPTA 2 mmol/l	Gd-BOPTA 4 mmol/l	Saline
With synovial fluid	Gd-DTPA 2 mmol/l		1244 ± 9	1481 ± 41	1598 ± 30	1529 ± 24	1412 ± 23	401 ± 8
		1246 ± 27	−0.2%	18.9%	28.3%	22.7%	13.3%	−67.8%
		1246 ± 27	P = 0.587	P < 0.001	P < 0.001	P < 0.001	P < 0.001	P < 0.001
Without synovial fluid			1188 ± 29	1412 ± 60	1525 ± 36	1466 ± 38	1353 ± 37	394 ± 10
		1275 ± 56	−6.8%	10.7%	19.6%	15.0%	6.1%	−69.1%
		1275 ± 56	P < 0.001	P < 0.001	P < 0.001	P < 0.001	P < 0.001	P < 0.001

Note. - P-values and percentages refer to comparison between the corresponding concentration of Gd-BOPTA and Gd-DTPA

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