Gadoxetate-enhanced dynamic contrast-enhanced MRI for evaluation of liver function and liver fibrosis in preclinical trials

Table 2 Correlation between the DCE-MRI indices and collagen area (%) and between the DCE-MRI indices and ICG-R15

MRI indices	Correlation with collagen area (%)			Correlation with ICG-R15
MRI indices	r^a	95% CI	p value	r^a	95% CI	p value
RLE-3	−0.80	−0.91 to − 0.57	< 0.001	− 0.62	− 0.82 to − 0.27	0.002
RLE-15	−0.51	−0.77 to − 0.12	0.015	−0.56	−0.80 to − 0.18	0.006
iAUC-3	−0.78	−0.90 to − 0.53	< 0.001	− 0.63	− 0.83 to − 0.28	0.002
iAUC-15	−0.81	−0.92 to − 0.58	< 0.001	− 0.65	− 0.84 to − 0.31	0.001
Emax	−0.81	−0.92 to − 0.59	< 0.001	− 0.58	− 0.80 to − 0.21	0.005

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