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Table 6 Comparison of Positive Predictive Value in Thyroid Nodules with Echogenic foci Types with different TIRADS Category Combination

From: Echogenic foci in thyroid nodules: diagnostic performance with combination of TIRADS and echogenic foci

Echogenic foci

TIRADS

PPV

TIRADS

PPV

P value

Type 1

Web-based TIRADS (≥ 8)

90.5

Web-based TIRADS (<  8)

32.2

< 0.001

K-TIRADS High Suspicion

87.8

K-TIRADSa

31.4

< 0.001

ATA High Suspicion

87.1

ATAa

20.0

< 0.001

Russ et al. (≥ 4B)

78.3

Russ et al. (< 4B)

27.8

< 0.001

Type 2

Web-based TIRADS (≥ 8)

91.9

Web-based TIRADS (<  8)

47.1

< 0.001

K-TIRADS High Suspicion

85.0

K-TIRADSa

57.1

0.579

ATA High Suspicion

84.8

ATAa

33.3

0.083

Russ et al. (≥ 4B)

83.0

Russ et al. (<4B)

42.9

0.036

Type 3

Web-based TIRADS (≥ 8)

90.9

Web-based TIRADS (< 8)

45.8

< 0.001

K-TIRADS High Suspicion

83.8

K-TIRADSa

38.6

< 0.001

ATA High Suspicion

84.2

ATAa

10.5

< 0.001

Russ et al. (≥ 4B)

73.5

Russ et al. (<4B)

37.8

< 0.001

Type 4

Web-based TIRADS (≥ 8)

50.0

Web-based TIRADS (<  8)

40.0

> 0.999

K-TIRADS High Suspicion

75.0

K-TIRADSa

34.8

0.237

ATA High Suspicion

75.0

ATAa

16.7

0.191

Russ et al. (≥ 4B)

66.7

Russ et al. (<4B)

33.3

0.187

Type 5

Web-based TIRADS (≥ 8)

66.7

Web-based TIRADS (< 8)

20.0

0.120

K-TIRADS High Suspicion

80.0

K-TIRADSa

18.8

0.025

ATA High Suspicion

80.0

ATAa

16.7

0.080

Russ et al. (≥ 4B)

66.7

Russ et al. (<4B)

20.0

0.120

Type 6

Web-based TIRADS (≥ 8)

90.5

Web-based TIRADS (<  8)

55.0

0.015

K-TIRADS High Suspicion

95.8

K-TIRADSa

41.2

< 0.001

ATA High Suspicion

96.0

ATAa

33.3

< 0.001

Russ et al. (≥ 4B)

89.3

Russ et al. (< 4B)

38.5

< 0.001

  1. TIRADS thyroid image reporting and data system, ATA american thyroid association, PPV positive predictive value
  2. aOther than High suspicion category
  3. TIRADS Thyroid image reporting and data system, ATA American Thyroid Association, PPV Positive Predictive Value
  4. Type 1 = Punctate echogenic foci (≤ 1 mm) with or without posterior shadowing
  5. Type 2 = Punctate echogenic foci with comet-tail artifact
  6. Type 3 = Large echogenic foci (> 1 mm) without shadowing
  7. Type 4 = Macrocalcification (defined as large echogenic foci (> 1 mm) with shadowing
  8. Type 5 = Peripheral curvilinear or eggshell echogenic foci with or without shadowing
  9. Type 6 = Nodules with more than one type of echogenic foci