Table 1 Baseline data of the granulomatosis with polyangiitis cohort
Total | Females | Males | |
|---|---|---|---|
Number of patients; n (%) | 121 (100) | 56 (100) | 65 (100) |
Demographics | |||
Age in years at diagnosis; median (range) | 46 (9 - 86) | 46 (13 - 78) | 47 (9 - 86) |
Age in years at baseline CT; median (range) | 49 (13 - 85) | 47 (13 - 79) | 49 (15 - 85) |
Years from diagnosis to baseline CT; median (range) | <1 (–7 - 25) | <1 (–7 - 25) | <1 (–4 - 21) |
Observation time in years; median (range) | 5.7 (1.1 - 15) | 5.2 (1.1 - 15) | 5.9 (1.2 - 15) |
Number of CT scans analysed per patient; median (range) | 5 (3 - 17) | 4.5 (3 - 14) | 5 (3 - 17) |
Clinical data | |||
PR3-ANCA; n (%) | 102 (84) | 43 (77) | 59 (91) |
MPO-ANCA; n (%) | 13 (11) | 9 (16) | 4 (6) |
Paranasal sinus surgery; n (%) | 33 (27) | 13 (23) | 20 (31) |
Local pain; n (%) | 39 (32) | 18 (32) | 21 (32) |
Nasal congestion; n (%) | 67 (55) | 29 (52) | 38 (58) |
Epistaxis; n (%) | 40 (33) | 15 (27) | 25 (38) |
Nasal crusts; n (%) | 30 (25) | 11 (20) | 19 (29) |
CT findings | |||
GOSS >0; n (%) | 58 (48) | 24 (43) | 34 (52) |
Destruction score >0; n (%) | 33 (27) | 12 (21) | 21 (32) |
LM-score >0; n (%) | 98 (81) | 40 (71) | 58 (89) |