Measuring liver fat fraction with complex-based chemical shift MRI: the effect of simplified sampling protocols on accuracy

Table 2 Table comparing freehand whole liver region of interest (ROI) and elliptical-ROIs for the right and left lobes performed by both observers demonstrated significant differences when tested with the Kruskal-Wallis test (P = 0.032 and 0.036)

Sampling method compared	Observer	Diff in median (IQR)	Mean difference (95% limits of agreement)	Coefficient of repeatability	Significance^a
Whole vs right ellipse	1	0.50 (0.29–0.99)	0.62 -0.58, 1.82	1.20	< 0.001
Whole vs right ellipse	2	0.56 (0.26–1.1)	0.80 -0.60, 2.19	1.39	< 0.001
Whole vs left ellipse	1	0.72 (0.36–1.56)	-0.32 - 3.18, 2.54	2.86	0.44
Whole vs left ellipse	2	0.71 (0.45–1.5)	-0.22 - 2.96, 2.51	2.74	0.52
Right vs left ellipse	1	1.15 (0.75–1.86)	-0.94 -4.40, 2.52	3.46	0.007
Right vs left ellipse	2	1.3 (0.60–1.89)	-1.01 -4.2, 2.17	3.19	0.001

^aPost-hoc paired Wilcoxon Rank Sum Test with Holm correction
Post-hoc tests revealed these differences to lie between freehand whole liver ROIs and elliptical right lobe ROIs and between the elliptical ROIs of the right and left lobes

ISSN: 1471-2342