Table 1 Levels of evidence^a

1

Independent, blinded comparison of the classifier with a biopsy-proven standard among a large number of consecutive lesions suspected of being the target condition

2

Independent, blinded comparison of the classifier with a biopsy-proven standard among a small number of consecutive lesions suspected of being the target condition

3

Independent, blinded comparison of the classifier with a biopsy-proven standard among non-consecutive lesions suspected of being the target condition

4

Non-independent comparison of the classifier with a biopsy-proven standard among obvious examples of the target condition plus benign lesions

5

Non-independent comparison of the classifier with a standard of uncertain validity