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Table 1 Hemodynamic parameters measured in the ascending aorta at rest and immediately following exercise stress from phase contrast acquisitions. Results are presented as the mean value plus or minus one standard deviation of the samples

From: MRI assessment of aortic flow in patients with pulmonary arterial hypertension in response to exercise

Variable

Rest

Stress

Young

Older

PAH

Young

Older

PAH

Heart rate [bpm]

66 ± 11

67 ± 9

69 ± 19

97 ± 19*

87 ± 12*

116 ± 19*

Stroke volume [mL]

96 ± 15

93 ± 16

67 ± 16

116 ± 23*

133 ± 40*

90 ± 42

Cardiac output [L/min]

6.3 ± 1.1

6.3 ± 1.6

4.5 ± 1.4

11 ± 2*

11.8 ± 5*

10.8 ± 5.7*

Peak systolic velocity [cm/s]

77 ± 21

58 ± 15

49 ± 14

78 ± 22

69 ± 27

68 ± 29*

Peak systolic flow [mL/s]

445 ± 85

416 ± 114

309 ± 52

446 ± 118

462 ± 176

388 ± 113

Relative area change

0.28 ± 0.08

0.17 ± 0.05

0.15 ± 0.05

0.28 ± 0.10

0.27 ± 0.14

0.25 ± 0.18

  1. *Denotes statistical significance (p < 0.05) relative to the same cohort at rest