Skip to main content

Table 1 Patient's characteristics

From: Quantification of liver iron overload disease with laser ablation inductively coupled plasma mass spectrometry

Cohort Diagnosis HFE Genetics* Sex Age Liver tissue Fe [μg/g] Serum Fe [μM] Transferrin
[mg/dL]
Ferritin
[μg/L]
Tranferrin saturation [%] Anonymised
Sample no.
Iron overload HFE HH Y282/Y282
H63/H63
M 61 1117 ND 138 1950 95 H4
Non-HFE HH C282/C282
H63/D63
M 55 2828 22.4 246 1850 36 H3
HFE HH Y282/Y282
H63/H63
F 60 7600 33.7 158 934 85 H1
HCV C282/C282
H63/H63
F 13 NID 21.4 246 52 35 H2
Normal iron status HBV, LTx ND M 59 NID 16.9 254 52 26 C4
Ductopenia, LTx ND F 69 NID 17.4 190 196 36 C1
LTx ND F 53 NID 21.0 297 64 28 C3
GvH ND M 36 NID 19.2 250 1431 31 C2
  1. Abbreviations used: F female, GvH graft-versus-host, HBV hepatitis B virus, HCV hepatitis C virus, HFE HH hereditary hemochromatosis, LTx liver transplantation, M male, NA not applicable, ND not determined, NID histologically no iron deposition, NN not known. Normal laboratory reference ranges are: hepatic Fe [μg/g dry weight]: 200-2400 (M), 400-1600 (F); serum Fe [μM]: 9-29 (M), 9-27 (F); Transferrin [mg/dL]: 200-400; Ferritin [μg/L]: 30-300 (M), 10-200 (F); Transferrin saturation [%]: 18-45. * HFE genotype constellations of patients subjected to LA-ICP-MS analysis were determined using TaqMan allelic discrimination assay [3, 9]