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Fig. 7 | BMC Medical Imaging

Fig. 7

From: Quantification of liver iron overload disease with laser ablation inductively coupled plasma mass spectrometry

Fig. 7

Simplified scheme of LA-ICP-MS workflow in imaging of iron overload. Metal imaging in the liver biopsy specimen requires seven steps including (1) the preparation of the cryosection with a precisely defined thickness (30 μm), (2) the light microscopic documentation of the section, (3) the LA-ICP-MS measurement itself, (4) data collection and compilation, (5) computation and validation of absolute or relative element concentration, (6) creation of colour-coded images of measured elements, and finally (7) data interpretation and making the concluding diagnosis “iron overload” or “no iron overload”, respectively

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