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Fig. 4 | BMC Medical Imaging

Fig. 4

From: Quantification of liver iron overload disease with laser ablation inductively coupled plasma mass spectrometry

Fig. 4

Metal imaging in liver specimen. Liver specimen with a thickness of 30 μm from each four HFE patients and healthy control subjects were analysed for content of carbon (C), sulfur (S), manganese (Mn), iron (Fe), copper (Cu), and zinc (Zn) by LA-ICP-MS. Individual images of elements were generated with the ELAI software tool. Light microscopic (LM) images of cryosections are depicted for orientation in the left margin (magnification × 4). The content of C used for normalization is given in %, while all other concentrations are given in μg/g liver tissue. More information about sample preparation, measurement, and data analysis are given in the Materials and Methods section. The precise parameters used in LA-ICP-MS measurement are summarized in Additional file 1: Table S1

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BMC Medical Imaging

ISSN: 1471-2342

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