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Table 1 Reproducibility of the cortical interruption parameters, and bone density and micro-structure parameters

From: An automated algorithm for the detection of cortical interruptions and its underlying loss of trabecular bone; a reproducibility study

  

Mean (SD)

ICC (95% CI)

SDRMS

LSCSD

CVRMS

LSCCV%

Cortical interruption parameters

      

Number of interruptions

 

3.1 (3.4)

0.82 (0.69 - 0.90)

1.5

4.2

n.a.

n.a.

Interruption surface

mm²

4.2 (7.1)

0.92 (0.85 - 0.96)

2.1

5.8

n.a.

n.a.

Interruption volume

mm³

3.5 (10.7)

0.99 (0.98 - 0.99)

1.1

3.2

n.a.

n.a.

Bone density parameters

 Tot.BMD

mg HA/cm³

341.8 (72.2)

1.00 (1.00 - 1.00)

3.8

10.6

1.1

3.2

 Tb.BMD

mg HA/cm³

163.4 (47.2)

0.99 (0.99 - 1.00)

3.6

10.0

2.6

7.3

 Ct.BMD

mg HA/cm³

883.7 (94.5)

1.00 (1.00 - 1.00)

4.5

12.4

0.5

1.4

 Ct.TMD

mg HA/cm³

939.8 (70.6)

1.00 (1.00 - 1.00)

3.3

9.1

0.4

1.0

Bone micro-structure parameters

 Tb.N

mmˉ¹

1.56 (0.49)

0.99 (0.98 - 0.99)

0.06

0.16

4.2

11.7

 Tb.Th

μm

90.7 (22.7)

0.98 (0.95 - 0.99)

3.6

10.1

4.3

11.8

 Tb.Sp

μm

630.4 (259.5)

0.98 (0.96 - 0.99)

39.6

109.7

4.4

12.1

 Tb.SpSD

μm

558.3 (316.2)

0.97 (0.95 - 0.99)

54.0

149.7

7.7

21.3

 Ct.Th

μm

889.7 (196.2)

1.00 (0.99 - 1.00)

15.1

41.8

1.4

3.9

 Ct.Po

%

4.31 (3.07)

1.00 (0.99 - 1.00)

0.35

0.96

8.7

24.1

 Ct.Po.Dm

μm

197.3 (86.3)

0.84 (0.72 - 0.91)

36.7

101.7

7.6

21.1

  1. Values are displayed as mean (SD), and for ICC as value (95% Confidence Interval)
  2. n.a. not applicable; CVRMS and LSCCV% were only determined for continuous variables
  3. ICC intra-class correlation coefficient, SD RMS root mean square of the standard deviation, LSC SD absolute least significant change, CV RMS root mean square of the coefficient of variation, LSC CV% least significant change in percentages, Tot.BMD total volumetric bone mineral density, Tb.BMD trabecular BMD, Ct.BMD cortical BMD, Ct.TMD cortical bone tissue BMD, Tb.N trabecular number, Tb.Th trabecular thickness, Tb.Sp trabecular separation, Tb.SpSD intra-individual distribution of trabecular separation, Ct.Th cortical thickness, Ct.Po cortical porosity, Ct.Po.Dm cortical porosity diameter