Table 3 Summary estimates from bivariate meta-analysis
From: The diagnostic performance of 18F-FAMT PET and 18F-FDG PET for malignancy detection: a meta-analysis
Summary estimates (95% CI) | Based on visual assessment | Based on diagnostic cut-off | ||
|---|---|---|---|---|
18F-FAMT | 18F-FDG | 18F-FAMT | 18F-FDG | |
Average Sensitivity | 80.7% (72.4–87.0%) | 88.8% (80.2–93.9%) | 74.1% (63.0–82.7%) | 78.3% (67.8–86.1%) |
p values | 0.181 | 0.542 | ||
Average Specificity | 60.7% (25.3–87.6%) | 29.2% (9.2–62.5%) | 84.4% (75.7–90.4%) | 68.1% (58.1–76.6%) |
p values | 0.207 | 0.009 | ||
Positive Likelihood | 2.46 (1.11–6.23) | 1.34 (1.00–2.25) | 4.90 (2.96–7.92) | 2.48 (1.81–3.44) |
Negative Likelihood | 0.36 (0.20–0.70) | 0.44 (0.20–0.98) | 0.31 (0.20–0.45) | 0.33 (0.20–0.49) |
DOR | 8.33 (1.60–26.10) | 3.88 (1.02–10.40) | 16.70 (7.25–33.40) | 8.19 (3.86–15.40) |
AUCa | 77.4% | 72.8% | 85.6% | 80.2% |
λ (mean accuracy) | 3.81 | 3.08 | 3.44 | 2.99 |