Fig. 1

Cine CMR images without and with endocardial contouring and examples of CMR-FT myocardial strain curves in mouse. A frame from cine image of the LV two-chamber view depicting LV and LA (a). The same LV two-chamber cine image after application of tissue tracking algorithm (b) and example of LV longitudinal strain curves obtained from two-chamber cine image (c). Cine image of LV short-axis view at mid-ventricular level before (d) and after (e) automatic endocardial border detection. An example of LV radial strain curves derived from short-axis cine image (f). LV = left ventricle; LA = left atrium; CMR-FT = cardiovascular magnetic resonance feature tracking