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Table 1 Pairwise comparison of ROI methods, by mean FA across both sides, per section of the optic tracts

From: Impact of region-of-interest method on quantitative analysis of DTI data in the optic tracts

Method 1

Method 2

Section 1

Section 2

Section 3

Mean (95 % CI)

p-value

Mean (95 % CI)

p-value

Mean (95 % CI)

p-value

FA-skeleton

Manual T1W

0.07 (0.03; 0.11)

<.0001

0.10 (0.06; 0.14)

<.0001

0.16 (0.11; 0.21)

<.0001

 

Manual b0

0.01 (−0.00; 0.03)

0.1501

0.01 (−0.01; 0.04)

0.4104

0.03 (−0.00; 0.07)

0.0559

 

Tractography

0.15 (0.10; 0.19)

<.0001

0.10 (0.04; 0.16)

0.0003

0.17 (0.12; 0.22)

<.0001

Manual T1W

Manual b0

−0.06 (−0.10; −0.01)

0.0047

−0.09 (−0.13; −0.04)

0.0001

−0.13 (−0.18; −0.07)

<.0001

 

Tractography

0.07 (0.02; 0.13)

0.0051

0.00 (−0.06; 0.06)

0.9999

0.01 (−0.04; 0.06)

0.9573

Manual b0

Tractography

0.13 (0.08; 0.18)

<.0001

0.09 (0.02; 0.15)

0.0046

0.14 (0.08; 0.20)

<.0001

  1. Pairwise difference in FA between ROI methods. Confidence intervals and p-values were corrected for multiplicity using the Tukey-Cramer method