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Fig. 4 | BMC Medical Imaging

Fig. 4

From: Magnetic resonance enterography changes after antibody to tumor necrosis factor (anti-TNF) alpha therapy in Crohn’s disease: correlation with SES-CD and clinical-biological markers

Fig. 4

Patient with CD of the distal ileum, left and transverse colon in treatment with IFX. At baseline, MRI (a and b) detected severe inflammatory lesions of the terminal ileum, with marked wall thickening accompanied by oedema, extensive irregularity of the mucosal surface and stratified hyperenhancement after intravenous contrast administration. A moderate wall thickening of the left colon is also present with hyperenhancement after intravenous contrast administration (Overall MaRIA score = 62,7). Baseline endoscopy at the distal ileum revealed the presence of stricturing, cobblestone appearance of the mucosal surface (c; SES-CD = 33). At week 26, the distal ileum continues to present at MRI a moderate wall thickening with mild hyperenhancement after intravenous contrast administration (d and e; Overall MaRIA score = 52,6; Δ MaRIA score = 10,1) Endoscopy of the same segment shows irregular longitudinal ulcers (f; SES-CD = 10)

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