Fig. 4
11C-acetate PET/CT imaging of MDR2−/−, MDR2−/+ and FVB wild type mice. 11C-acetate PET/CT imaging was performed on 12 mo MDR2−/− and FVB control mice. a) Representative 11C-acetate PET/CT parametric (ml/g.min) images of MDR2−/− mouse. b) Representative 11C-acetate PET/CT parametric (ml/g.min) images of FVB control mouse. c) Hepatic 11C-acetate metabolic rate was significantly greater in MDR2−/− mouse when compared to controls (student’s t test p < 0.05, n = 3/group)