Figure 3

Validity of intracranial volume estimates. The validity of intracranial volume (ICV) estimates compared to the ICV segmentations is given by percentile curves (95^th, 75^th, 50^th, 25^th and 5^th percentile) for piecewise constant interpolation (black graphs), piecewise linear interpolation (purple graphs) and cubic spline interpolation (blue graphs). The percentiles are calculated for intra-class correlation coefficients (first column), Pearson’s correlation (second column), Jaccard index (third column), and percentage errors (fourth column). Besides interpolation method the validity of the estimates depends upon the linear spacing between intracranial areas (X-axis) and orientation of the intracranial areas, either coronal (first row), sagittal (second row) or transversal (third row).