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Table 4 Studies comparing MRCP and ERCP with final diagnosis

From: MRCP compared to diagnostic ERCP for diagnosis when biliary obstruction is suspected: a systematic review

Study Definition of Final diagnosis Sensitivity Specificity
   MRCP vs. final diagnosis ERCP vs. final diagnosis* MRCP vs. final diagnosis ERCP vs. final diagnosis*
Adamek[9] ERCP plus histological findings or follow-up 42/47 for any abnormality
0.89 (CI: 0.77–0.95)
22/27 for malignancy
0.81 (CI: 0.63–0.92)
0.91 for any abnormality
0.93 for malignancy
12/13
0.92 (CI: 0.67–0.99) for any abnormality
33/33
1.00 (CI: 0.90–1.00) for malignancy
0.92 for any abnormality
0.94 for malignancy
Laokpessi[21] Stone extraction with ERCP or IOC 105/113
0.93 (CI: 87–0.96) for Choledocholithiasis
78/81
0.95 (CI: 0.87–0.98)
34/34
1.00 (CI: 0.90–1.00)
19/19
1.00 (CI: 0.79–1.00)
Lee[22] ERCP plus surgical findings 17/21 for malignancy
0.81 (CI: 0.60–0.92)
15/21
0.71 (CI: 0.50–0.86)
23/25
0.92 (CI: 0.75–0.98)
23/24
0.96 (CI: 0.80 to 0.99)
Regan[26] ERCP, endoscopic balloon or basket extraction or surgical removal of stones 14/15
0.93 (CI: 0.70–0.99) for choledocholithiasis
15/15
1.00 (CI: 0.80–1.00)
7/8
0.88 (CI: 0.53–0.98)
8/8
1.00 (CI: 0.68–1.00)
  1. *Raw data was not reported in some studies, therefore it is not clear whether are not the two groups (MRCP vs. final diagnosis and ERCP vs. final diagnosis) are directly comparable.