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Table 2 Shape of the treatment zone

From: Specific CT 3D rendering of the treatment zone after Irreversible Electroporation (IRE) in a pig liver model: the “Chebyshev Center Concept” to define the maximum treatable tumor size

 

Circularity

Sphericity

 

Technique A1

Technique B2

Technique A1

Technique B2

Protocol 13

0.4 ± 0.1#,*

0.6 ± 0.3#,**

1.7 ± 0.3+,***

1.0 ± 0.2+,****

(0.3 - 0.5)

(0.3 - 0.8)

(1.3 - 2.0)

(0.7 - 1.2)

Protocol 24

0.7 ± 0.1##,*

0.7 ± 0.2##,**

1.4 ± 0.2++,***

0.9 ± 0.1++,****

(0.5 - 0.9)

(0.4 - 0.9)

(1.2 - 1.7)

(0.7 - 1.0)

Protocol 35

0.5 ± 0.2###,*

0.8 ± 0.1###,**

1.6 ± 0.2+++,***

0.9 ± 0.1+++,****

 

(0.3 - 0.7)

(0.7 - 0.8)

(1.4 - 1.9)

(0.8 - 0.9)

  1. 1semi-automated software prototype for CT 3d rendering with the “Chebyshev Center Concept” implemented;
  2. 2standard CT 3d analysis;
  3. 3Protocol 1 with n = 5 IREs (three applicators, tip exposure of 20 mm, distance between pairs of applicators of 15 mm, pulse number of 90, pulse length of 90 μs, and electric field of 1500 V/cm);
  4. 4Protocol 2 with n = 5 IREs (three applicators, tip exposure of 25 mm, distance between pairs of applicators of 20 mm, pulse number of 90, pulse length of 90 μs, and electric field of 1500 V/cm);
  5. 5Protocol 3 with n = 5 IREs (six applicators, tip exposure of 30 mm, distance between pairs of applicators of 15 mm, pulse number of 70, pulse length of 90 μs, and electric field of 1400 V/cm);
  6. statistical differences between Technique A and Technique B were analyzed with the Wilcoxon signed-rank test: #p > 0.05; ##p > 0.05; ###p < 0.01; +p < 0.01; ++p < 0.01; +++p < 0.01;
  7. statistical differences between Protocol 1, Protocol 2 and Protocol 3 were analyzed with non-parametric Kruskal-Wallis test: *p > 0.05; **p > 0.05; ***p > 0.05; ****p > 0.05.