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Table 1 Size of the treatment zone

From: Specific CT 3D rendering of the treatment zone after Irreversible Electroporation (IRE) in a pig liver model: the “Chebyshev Center Concept” to define the maximum treatable tumor size

 

Long diameter (mm)

Intermediate diameter (mm)

Short diameter (mm)

 

Technique A1

Technique B2

Technique A1

Technique B2

Technique A1

Technique B2

Protocol 13

42.1 ± 3.2#,*

37.5 ± 10.2#,**

30.1 ± 3.2+,***

27.9 ± 5.5+,****

17.2 ± 6.0°,*****

19.9 ± 4.6°,******

(39.3 - 47.2)

(29.4 - 48.6)

(26.6 - 33.7)

(22.0 - 32.7)

(10.9 - 24.4)

(15.4 - 26.4)

Protocol 24

43.7 ± 8.6##,*

43.8 ± 3.9##,**

35.7 ± 8.2++,***

37.1 ± 6.2++,****

27.9 ± 4.2°°,*****

31.1 ± 10.5°°,******

(30.4 – 52.8)

(40.1 - 50.2)

(26.1 – 44.8)

(30.6 - 46.0)

(25.3 - 35.3)

(17.5 - 42.1)

Protocol 35

74.5 ± 6.1###,*

71.0 ± 3.4###,**

56.3 ± 5.3+++,***

56.3 ± 2.9+++,****

41.1 ± 13.1°°°,*****

53.8 ± 1.1°°°,******

 

(63.7 - 78.1)

(67.3 - 75.1)

(47.2 - 60.1)

(52.7 - 59.2)

(20.7 - 52.6)

(52.4 - 54.9)

  1. 1semi-automated software prototype for CT 3d rendering with the “Chebyshev Center Concept” implemented;
  2. 2standard CT 3d analysis;
  3. 3Protocol 1 with n = 5 IREs (three applicators, tip exposure of 20 mm, distance between pairs of applicators of 15 mm, pulse number of 90, pulse length of 90 μs, and electric field of 1500 V/cm);
  4. 4Protocol 2 with n = 5 IREs (three applicators, tip exposure of 25 mm, distance between pairs of applicators of 20 mm, pulse number of 90, pulse length of 90 μs, and electric field of 1500 V/cm);
  5. 5Protocol 3 with n = 5 IREs (six applicators, tip exposure of 30 mm, distance between pairs of applicators of 15 mm, pulse number of 70, pulse length of 90 μs, and electric field of 1400 V/cm);
  6. statistical differences between Technique A and Technique B were analyzed with the Wilcoxon signed-rank test: #p > 0.05; ##p > 0.05; ###p > 0.05; +p > 0.05; ++p > 0.05; +++p > 0.05; °p > 0.05; °°p > 0.05; °°°p < 0.05;
  7. statistical differences between Protocol 1, Protocol 2 and Protocol 3 were analyzed with the non-parametric Kruskal-Wallis test: *p < 0.01; **p < 0.01; ***p < 0.01; ****p < 0.005; *****p < 0.01; ******p < 0.005.