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Table 2 ADC and ADC-R characteristics of 128 prostatic sectors for low- and intermediate-risk group (Gleason 6 and 7) and high-risk group (Gleason 8 and 9)

From: Evaluation of the normal-to-diseased apparent diffusion coefficient ratio as an indicator of prostate cancer aggressiveness

Biopsy specimen characteristics

Gleason 6 and 7 (n = 51)

Gleason 8 and 9 (n = 77)

p

*Number of patients

14 (64%)

8 (36%)

 

Age (years)

66 (56–76)

59 (46–76)

<0.001

PSA (ng/mL)

10.74 (3.5-25)

26 (14–100)

<0.001

ADC (mm2/sec)

0.88 × 10-3 ± 0.13

0.73 × 10-3 ± 0.17

<0.001

Normal central zone ADC (mm2/sec)

1.38 × 10-3 ± 0.24

1.59 × 10-3 ± 0.22

<0.001

Normal peripheral zone ADC (mm2/sec)

1.64 × 10-3 ± 0.19

1.90 × 10-3 ± 0.35

<0.001

ADC-CR

0.66 ± 0.17

0.48 ± 0.13

<0.001

ADC-PR

0.54 ± 0.09

0.41 ± 0.09

<0.001

  1. Note: Data are presented as mean and standard deviation or median and range, except where indicated. *: Data are presented as number and percentages. ADC-CR: ratio between tumor ADCs and healthy central gland tissue ADCs. ADC-PR: ratio between tumor ADCs and healthy peripheral zone tissue ADCs.