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Figure 3 | BMC Medical Imaging

Figure 3

From: The use of high-frequency ultrasound imaging and biofluorescence for in vivoevaluation of gene therapy vectors

Figure 3

Ex vivo callipers and HF-US correlated well to tumour mass. Final tumour mass correlated most strongly with ex vivo calliper volume. Pearson correlations showed that in vivo calliper volumes correlated the least with tumour mass (Figure 3 a, R2 = 0.7843, 95% CI = 0.4811-0.9792, p = 0.0034), followed by HF-US volume (Figure 3 b, R2 = 0.8470, 95% CI = 0.6135-0.9857, p = 0.0012) whereas ex vivo calliper volume showed the best correlation (Figure 3 c, R2 = 0.9254, 95% CI = 0.7580-0.9946, p = 0.0005). Smaller tumours were not accurately weighed by the balance therefore n = 8.

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