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Figure 2 | BMC Medical Imaging

Figure 2

From: The use of high-frequency ultrasound imaging and biofluorescence for in vivoevaluation of gene therapy vectors

Figure 2

HF-US correlates more closely to the ex vivo tumour volume than using mechanical callipers in vivo . The tumour volume generated by HF-US correlates more closely with the final ex vivo calliper volume than the in vivo calliper volume. (a) The Pearson correlation plot of HF-US volumes versus ex vivo volumes has a higher R2 value (R2 = 0.7993, 95% CI = 0.6342-0.9724,p = 0.0002, two-tailed) than in vivo calliper volumes versus ex vivo volumes (b) (R2 = 0.7867, 95% CI = 0.5421-0.9761, p = 0.0014, two-tailed). The solid line denotes line of best fit and dotted lines indicate the 95% confidence band, n = 10.

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