Figure 1From: Correlation between the area of high-signal intensity on SPIO-enhanced MR imaging and the pathologic size of sentinel node metastases in breast cancer patients with positive sentinel nodes Sentinel node localization using CT-lymphography and SPIO-enhanced MR imaging for diagnosis. Three-dimensional CT-lymphography reconstructed from the first post-contrast images (a). Lymphatic vessels drained into a single axillary sentinel node (arrow). Images of CT-lymphography (b) and T2*-weighted axial MR images (c) at the same level were compared to specify the node (arrow) on T2*-weighted axial MR imaging corresponding to the sentinel node (arrow) identified by CT-lymphography. The node (arrow) showed high-signal intensity before administration of superparamagnetic iron oxide (SPIO). (d) After administration of SPIO, the node showed homogenous low signal intensity and was diagnosed as benign (arrow).Back to article page