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Table 1 Quantitative video intensity for ultrasound contrast agent targeted with isotype control antibody (UCA IGg ) and anti-VEGFR2 monoclonal antibody (UCA VEGFR2 )

From: Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice

  Normal thyroid (n.4) Hyperplasia/Benign nodules (n.5) Thyroid carcinoma (n.7)
Video intensity UCAIGg  
  Video intensity difference 11.3 (9.4-14.7) 12.2 (8.5-19.6) 19.4 (11.4-22.6)
Video intensity UCAVEGFR2  
  Video intensity difference 10.9 (10.3-14.9) 13.3 (10.8-15.8) 30.1 (25.1-35.6)* §
  1. * Statistical significant difference between Thyroid carcinoma and normal thyroid or Hyperplasia/benign nodules p<0.05.
  2. § Statistical significant difference between UCA targeted with anti-VEGFR2 monoclonal antibody and isotype control antibody p=0.0156.