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Table 1 Quantitative video intensity for ultrasound contrast agent targeted with isotype control antibody (UCA IGg ) and anti-VEGFR2 monoclonal antibody (UCA VEGFR2 )

From: Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice

 

Normal thyroid (n.4)

Hyperplasia/Benign nodules (n.5)

Thyroid carcinoma (n.7)

Video intensity UCAIGg

 

  Video intensity difference

11.3 (9.4-14.7)

12.2 (8.5-19.6)

19.4 (11.4-22.6)

Video intensity UCAVEGFR2

 

  Video intensity difference

10.9 (10.3-14.9)

13.3 (10.8-15.8)

30.1 (25.1-35.6)* §

  1. * Statistical significant difference between Thyroid carcinoma and normal thyroid or Hyperplasia/benign nodules p<0.05.
  2. § Statistical significant difference between UCA targeted with anti-VEGFR2 monoclonal antibody and isotype control antibody p=0.0156.