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Table 1 Results of neurobehavioral testing in animals that received either In-111-oxine or 3 million In-111-labeled hUTC (In-111 hUTC) 48 hours post-tMCAo

From: Tracking of In-111-labeled human umbilical tissue-derived cells (hUTC) in a rat model of cerebral ischemia using SPECT imaging

 

mNSS score

Adhesive removal time score (sec)

% Left foot-fault score

Days

In-111 oxine

In-111 hUTC

In-111 oxine

In-111 hUTC

In-111 oxine

In-111 hUTC

 

Mean±SD(n)

Mean±SD(n)

Mean±SD(n)

Mean±SD(n)

Mean±SD(n)

Mean±SD(n)

1

11.2±0.63(10)

11.5±0.52(11)

115.4±5.18(10)

117.0±4.34(11)

36.6±3.24(10)

36.5±3.30(11)

7

―

―

―

―

―

―

14

9.0±0.94(10)

8.5±0.69(11)

104.2±3.83(10)

100.4±6.83(11)

25.5±3.44(10)

24.3±2.94(11)

21

7.7±0.82(10)

6.9±0.54(11)*

91.1±9.88(10)

85.3±9.64(11)*

19.6±3.13(10)

17.4±3.11(11)*

28

7.2±0.79(10)

6.3±0.65(11)*

79.2±6.38(10)

66.0±9.95(11)*

17.9±2.64(10)

15.5±2.62(11)*

35

6.5±0.85(10)

5.5±0.69(11)*

71.1±5.11(10)

58.7±8.10(11)*

15.6±2.01(10)

13.5±1.81(11)*

42

6.2±0.79(10)

5.4±0.50(11)*

50.4±6.27(10)

41.3±9.31(11)*

14.0±2.49(10)

12.0±1.55(11)*

49

6.0±0.67(10)

5.1±0.30(11)*

45.6±6.83(10)

35.6±8.39(11)*

13.0±2.49(10)

11.0±1.34(11)*

56

5.6±0.52(10)

4.9±0.30(11)*

31.9±11.10(10)

21.5±9.25(11)*

12.2±2.39(10)

10.3±1.19(11)*

70

5.6±0.52(10)

4.8±0.60(11)*

78.4±13.76(10)

62.4±13.77(11)*

11.3±1.77(10)

9.9±1.14(11)*

84

5.4±0.52(10)

4.6±0.50(11)*

71.0±14.50(10)

45.2±6.73(11)*

10.9±1.91(10)

8.6±1.12(11)*

90

5.4±0.52(10)

4.6±0.50(11)*

61.3±12.73(10)

35.4±6.43(11)*

10.2±1.55(10)

8.5±0.93(11)*

  1. The dada are expressed in mean±SD. Number of animals are indicated within parenthesis. * = significant differences.