Figure 2

The ROI sets from two raters are shown for a FLAIR MRI slice of a patient with MS. The blue ROIs are from one rater and the red ROIs are from the other. The ROIs in green designate where the two raters drew the exact same ROIs. Clockwise, starting from the upper left most lesion, the sizes of the lesions were: 106.7, 131.8; 58.0, 58.0; 32.1, 32.1; 27.7, 27.7; 174.7, 224.0; 507.9, 574.6; 10.6,0; and 28.9, 0 mm² for the Red and Blue raters‘ ROIs, respectively; the green ROIs were included as both Red and Blue ROIs, and 0 is used when the rater didn’t draw an ROI at that location. Although DE and OER are calculated for an entire volume, for demonstration, we find DE for this slice is 39.5 mm² and OER for this slice is .142.