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Table 3 Influence of partial volume effect on volume determination. The maximum possible influence of the partial volume effect (PVE) on tumour volume estimations, assuming isotropic voxels and a spherical tumour, determined by simulations

From: Tumour size measurement in a mouse model using high resolution MRI

Voxels/diameter(mm−1) Maximum relative volume difference (%)
overestimated underestimated
70 6 −6
45 10 −10
28 16 −14
12 39 −31
  1. The voxels-per-tumour-diameter ratio is listed with the corresponding results from the simulation. The relative difference between over- and underestimated tumour volumes and the analytically calculated volume are given as a percentage of true tumour volume.