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Figure 7 | BMC Medical Imaging

Figure 7

From: Quantitative metric profiles capture three-dimensional temporospatial architecture to discriminate cellular functional states

Figure 7

The most significant metrics capture structural differences to generate a unique metric profile for each cell type. 7a plots the raw data and standard deviation bars of the most important metrics from the generated cell-graphs for each cell type over time. Due to the scale of the graphs in 7a it is difficult to see small changes in metric values, however these changes are captured by the percent changes shown in 7b. 7b was generated by first calculating the averages of the data points in 7a at hour 10 and 16 for each sample as well as the averages for the data points at hours 120 and 168 (the first and last two time points in the graphs, respectively). These averages were then used to determine the percent change of each metric for each cell type over time. The key to 7b shows how arrows represent varying degrees of percent change in the table. Figure 7c shows the results of the combination of two-sample Kolmogorov-Smirnov test results for the five most significant metrics. The cell-line pairs that belong to similar probability distributions are shown with black squares. Note that the cell-lines are in exact agreement with themselves.

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