Articles

Kinematic analysis of diastolic function using the freely available software Echo E-waves – feasibility and reproducibility

Early diastolic left ventricular (LV) filling can be accurately described using the same methods used in classical mechanics to describe the motion of a loaded spring as it recoils, a validated method also ref...

Authors: Martin G. Sundqvist, Katrin Salman, Per Tornvall and Martin Ugander

Characterization of ten white matter tracts in a representative sample of Cuban population

The diffusion tensor imaging technique (DTI) combined with tractography methods, has achieved the tridimensional reconstruction of white matter tracts in the brain. It allows their characterization in vivo in ...

Authors: D. Góngora, M. Domínguez and M. A. Bobes

¹⁸F-FDG uptake in the stomach on screening PET/CT: value for predicting Helicobacter pylori infection and chronic atrophic gastritis

The aim of this study was to determine the value of ¹⁸F-FDG uptake on screening PET/CT images for the prediction of Helicobacter pylori (H. pylori) infection and chronic atrophic gastritis.

Authors: Shigeki Kobayashi, Mayumi Ogura, Naohisa Suzawa, Noriyuki Horiki, Masaki Katsurahara, Toru Ogura and Hajime Sakuma

Mapping breast tissue types by miniature radio-frequency near-field spectroscopy sensor in ex-vivo freshly excised specimens

Receiving real-time information on tissue properties while performing biopsy procedures has the potential of improving biopsy accuracy. The study goal was to test the ability of a miniature flexible Radio-Freq...

Authors: Zvi Kaufman, Haim Paran, Ilana Haas, Patricia Malinger, Tania Zehavi, Tamar Karni, Izhak Pappo, Judith Sandbank, Judith Diment and Tanir Allweis

The effect of intramuscular interferon beta-1a on spinal cord volume in relapsing-remitting multiple sclerosis

Spinal cord atrophy occurs early in multiple sclerosis (MS) and impacts disability. The therapeutic effect of interferon beta-1a (IFNβ-1a) on spinal cord atrophy in patients with relapsing-remitting (RR) MS ha...

Authors: Sheena L. Dupuy, Fariha Khalid, Brian C. Healy, Sonya Bakshi, Mohit Neema, Shahamat Tauhid and Rohit Bakshi

A deformable template method for describing and averaging the anatomical variation of the human nasal cavity

Understanding airflow through human airways is of importance in drug delivery and development of assisted breathing methods. In this work, we focus on development of a new method to obtain an averaged upper ai...

Authors: Alireza Nejati, Natalia Kabaliuk, Mark C. Jermy and John E. Cater

How to assess intra- and inter-observer agreement with quantitative PET using variance component analysis: a proposal for standardisation

Quantitative measurement procedures need to be accurate and precise to justify their clinical use. Precision reflects deviation of groups of measurement from another, often expressed as proportions of agreemen...

Authors: Oke Gerke, Mie Holm Vilstrup, Eivind Antonsen Segtnan, Ulrich Halekoh and Poul Flemming Høilund-Carlsen

Differences in sex distribution, anatomic location and MR imaging appearance of pediatric compared to adult chordomas

Chordomas are rare malignancies that primarily affect adults, but also rarely affect pediatric patients. We compared the imaging appearance, demographic and anatomic distributions of adult and pediatric chordo...

Authors: Ronnie Sebro, Thomas DeLaney, Francis Hornicek, Joseph Schwab, Edwin Choy, G. Petur Nielsen and Daniel I. Rosenthal

Applying a computer-aided scheme to detect a new radiographic image marker for prediction of chemotherapy outcome

To investigate the feasibility of automated segmentation of visceral and subcutaneous fat areas from computed tomography (CT) images of ovarian cancer patients and applying the computed adiposity-related image...

Authors: Yunzhi Wang, Yuchen Qiu, Theresa Thai, Kathleen Moore, Hong Liu and Bin Zheng

Sparse reconstruction of compressive sensing MRI using cross-domain stochastically fully connected conditional random fields

Magnetic Resonance Imaging (MRI) is a crucial medical imaging technology for the screening and diagnosis of frequently occurring cancers. However, image quality may suffer from long acquisition times for MRIs ...

Authors: Edward Li, Farzad Khalvati, Mohammad Javad Shafiee, Masoom A. Haider and Alexander Wong

Multimodal MRI for early diabetic mild cognitive impairment: study protocol of a prospective diagnostic trial

Type 2 diabetes mellitus (T2DM) is a risk factor for dementia. Mild cognitive impairment (MCI), an intermediary state between normal cognition and dementia, often occurs during the prodromal diabetic stage, ma...

Authors: Ying Yu, Qian Sun, Lin-Feng Yan, Yu-Chuan Hu, Hai-Yan Nan, Yang Yang, Zhi-Cheng Liu, Wen Wang and Guang-Bin Cui

The effect of patient anxiety and depression on motion during myocardial perfusion SPECT imaging

Patient motion during myocardial perfusion SPECT imaging (MPI) may be triggered by a patient’s physical and/or psychological discomfort. The aim of this study was to investigate the impact of state anxiety (pa...

Authors: Vassiliki Lyra, Maria Kallergi, Emmanouil Rizos, Georgios Lamprakopoulos and Sofia N. Chatziioannou

Color radiography in lung nodule detection and characterization: comparison with conventional gray scale radiography

To compare the capability of lung nodule detection and characterization between dual-energy radiography with color-representation (DCR) and conventional gray scale chest radiography (GSR).

Authors: Inyoung Song, Jeong Geun Yi, Jeong Hee Park, Kyung Soo Lee and Myung Jin Chung

Evaluation of energy spectrum CT for the measurement of thyroid iodine content

This study aims to provide a reference for the diagnosis of iodine deficiency disorder by evaluating the normal thyroid iodine content by energy spectrum computed tomography (CT) and calculating the iodine con...

Authors: Weiguang Shao, Jingang Liu and Dianmei Liu

Validation of T1 and T2 algorithms for quantitative MRI: performance by a vendor-independent software

Determination of the relaxation time constants T1 and T2 with quantitative magnetic resonance imaging is increasingly used for both research and clinical practice. Recently, groups have been formed within the ...

Authors: Sebastian Bidhult, George Kantasis, Anthony H. Aletras, Håkan Arheden, Einar Heiberg and Erik Hedström

Counter-clockwise vortical blood flow in the main pulmonary artery in a patient with patent ductus arteriosus with pulmonary arterial hypertension: a cardiac magnetic resonance imaging case report

In patients with pulmonary hypertension (PH), duration of vortical blood flow along the main pulmonary artery enables estimation of the mean pulmonary arterial pressure (mPAP) non-invasively. It remains to dat...

Authors: Gert Reiter, Ursula Reiter, Gabor Kovacs, Gabriel Adelsmayr, Andreas Greiser, Aurelien F. Stalder, Horst Olschewski and Michael Fuchsjäger

Reliability of radiographic measurements for acute distal radius fractures

The management of distal radial fractures is guided by the interpretation of radiographic findings. The aim of this investigation was to determine the intra- and inter-observer reliability of eight traditional...

Authors: Narelle J. Watson, Saeed Asadollahi, Frank Parrish, Jacqueline Ridgway, Phong Tran and Jennifer L. Keating

Evaluation of dynamic infrared thermography as an alternative to CT angiography for perforator mapping in breast reconstruction: a clinical study

The current gold standard for preoperative perforator mapping in breast reconstruction with a DIEP flap is CT angiography (CTA). Dynamic infrared thermography (DIRT) is an imaging method that does not require ...

Authors: Sven Weum, James B. Mercer and Louis de Weerd

Impact of region-of-interest method on quantitative analysis of DTI data in the optic tracts

To extract DTI parameters from a specific structure, a region of interest (ROI) must be defined. ROI selection in small structures is challenging; the final measurement results could be affected due to the sig...

Authors: Ylva Lilja, Oscar Gustafsson, Maria Ljungberg, Daniel Nilsson and Göran Starck

Radiation dosimetry of 18F-FDG PET/CT: incorporating exam-specific parameters in dose estimates

Whole body fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) is the standard of care in oncologic diagnosis and staging, and patient radiation dose must be well understoo...

Authors: Brian Quinn, Zak Dauer, Neeta Pandit-Taskar, Heiko Schoder and Lawrence T. Dauer

A statistical shape modelling framework to extract 3D shape biomarkers from medical imaging data: assessing arch morphology of repaired coarctation of the aorta

Medical image analysis in clinical practice is commonly carried out on 2D image data, without fully exploiting the detailed 3D anatomical information that is provided by modern non-invasive medical imaging tec...

Authors: Jan L. Bruse, Kristin McLeod, Giovanni Biglino, Hopewell N. Ntsinjana, Claudio Capelli, Tain-Yen Hsia, Maxime Sermesant, Xavier Pennec, Andrew M. Taylor and Silvia Schievano

Osteoblastic lesion screening with an advanced post-processing package enabling in-plane rib reading in CT-images

To evaluate screening and diagnostic accuracy for the detection of osteoblastic rib lesions using an advanced post-processing package enabling in-plane rib reading in CT-images.

Authors: Hannes Seuss, Peter Dankerl, Alexander Cavallaro, Michael Uder and Matthias Hammon

Development of a morphology-based modeling technique for tracking solid-body displacements: examining the reliability of a potential MRI-only approach for joint kinematics assessment

Single or biplanar video radiography and Roentgen stereophotogrammetry (RSA) techniques used for the assessment of in-vivo joint kinematics involves application of ionizing radiation, which is a limitation for cl...

Authors: Niladri K. Mahato, Stephane Montuelle, John Cotton, Susan Williams, James Thomas and Brian Clark

Magnetic resonance enterography changes after antibody to tumor necrosis factor (anti-TNF) alpha therapy in Crohn’s disease: correlation with SES-CD and clinical-biological markers

In recent years, the use of MRI in patients with Crohn’s disease (CD) has increased. However, few data are available on how MRI parameters of active disease change during treatment with anti-TNF and whether th...

Authors: Luca Pio Stoppino, Nicola Della Valle, Stefania Rizzi, Elsa Cleopazzo, Annarita Centola, Donatello Iamele, Christos Bristogiannis, Giuseppe Stoppino, Roberta Vinci and Luca Macarini

A case of intra-articular ganglion cysts of the knee joint: correlation between arthroscopic and magnetic resonance imaging

Intra-articular ganglion cysts of the knee are rare. Here we report a case of an arthroscopically confirmed ganglion cyst arising from the posterior cruciate ligament (PCL) along with preoperative magnetic res...

Authors: Sayaka Kodaira, Takahito Nakajima, Ryosuke Takahashi, Shingo Moriya, Tomoyuki Nakagawa, Hidenori Ohtake and Yoshito Tsushima

Current T₁ and T₂ mapping techniques applied with simple thresholds cannot discriminate acute from chronic myocadial infarction on an individual patient basis: a pilot study

Studying T₁- and T₂-mapping for discrimination of acute from chronic myocardial infarction (AMI, CMI).

Authors: Florian von Knobelsdorff-Brenkenhoff, Marcel Prothmann, Matthias A. Dieringer, Ralf Wassmuth, André Rudolph, Wolfgang Utz, Julius Traber, Andreas Greiser, Thoralf Niendorf and Jeanette Schulz-Menger

Quantification of maceration changes using post mortem MRI in fetuses

Post mortem imaging is playing an increasingly important role in perinatal autopsy, and correct interpretation of imaging changes is paramount. This is particularly important following intra-uterine fetal deat...

Authors: P. Montaldo, S. Addison, V. Oliveira, P. J. Lally, A. M. Taylor, N. J. Sebire, S. Thayyil and O. J. Arthurs

Erratum to: prostate cancer arising in ectopic prostatic tissue within the left seminal vesicle: a rare case diagnosed with multi-parametric magnetic resonance imaging and magnetic resonance imaging-transrectal ultrasound fusion biopsy

Authors: Alexander S. Somwaru, Deepu Alex and Atif Zaheer

Practical one-dimensional measurements of age-related brain atrophy are validated by 3-dimensional values and clinical outcomes: a retrospective study

Age-related brain atrophy has been represented by simple 1-dimensional (1-D) measurements on computed tomography (CT) for several decades and, more recently, with 3-dimensional (3-D) analysis, using brain volu...

Authors: C. Michael Dunham, Albert J. Cook II, Alaina M. Paparodis and Gregory S. Huang

Anisakiasis mimics cancer recurrence: two cases of extragastrointestinal anisakiasis suspected to be recurrence of gynecological cancer on PET-CT and molecular biological investigation

We report two cases of anisakiasis lesions that were initially suspected to be recurrence of gynecological cancer by positron emission tomography-computed tomography (PET-CT). Both cases were extragastrointest...

Authors: Yuya Nogami, Yoko Fujii-Nishimura, Kouji Banno, Atsushi Suzuki, Nobuyuki Susumu, Taizo Hibi, Koji Murakami, Taketo Yamada, Hiromu Sugiyama, Yasuyuki Morishima and Daisuke Aoki

3D rotational fluoroscopy for intraoperative clip control in patients with intracranial aneurysms – assessment of feasibility and image quality

Mobile 3D fluoroscopes have become increasingly available in neurosurgical operating rooms. In this series, the image quality and value of intraoperative 3D fluoroscopy with intravenous contrast agent for the ...

Authors: Thomas Westermaier, Thomas Linsenmann, György A. Homola, Mario Loehr, Christian Stetter, Nadine Willner, Ralf-Ingo Ernestus, Laszlo Solymosi and Giles H. Vince

Clinical value of endoluminal ultrasonography in the diagnosis of rectovaginal fistula

Rectovaginal fistula (RVF) refers to a pathological passage between the rectum and vagina, which is a public health challenge. This study was aimed to explore the clinical value of endoluminal biplane ultrason...

Authors: Hao-Qiang Yin, Chen Wang, Xin Peng, Fang Xu, Ya-Juan Ren, Yong-Qing Chao, Jin-Gen Lu, Song Wang and Hu-Sheng Xiao

Pelvic retroperitoneal pleomorphic hyalinizing angiectatic tumor (PHAT) of soft tissue: a case report

Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare soft tissue tumor of low malignant potential, which most often arises in the lower extremities. Lesions occurred in other anatomic locations have been...

Authors: Zhi-gang Chu, Meng-qi Liu, Zhi-yu Zhu, Fa-jin Lv and Yu Ouyang

The correlation between radiographic and pathologic grading of lumbar facet joint degeneration

Before performing spine non-fusion surgery that retains the facet joints, choosing an accurate radiographic method to evaluate the degree of facet joint degeneration is extremely important. Therefore, the obje...

Authors: Xin Zhou, Yuan Liu, Song Zhou, Xiao-Xing Fu, Xiao-Long Yu, Chang-Lin Fu, Bin Zhang and Min Dai

Phase-contrast MRI volume flow – a comparison of breath held and navigator based acquisitions

Magnetic Resonance Imaging (MRI) 2D phase-contrast flow measurement has been regarded as the gold standard in blood flow measurements and can be performed with free breathing or breath held techniques. We hypo...

Authors: Charlotta Andersson, Johan Kihlberg, Tino Ebbers, Lena Lindström, Carl-Johan Carlhäll and Jan E. Engvall

- LAA Occluder View for post-implantation Evaluation (LOVE) - standardized imaging proposal evaluating implanted left atrial appendage occlusion devices by cardiac computed tomography

A standardized imaging proposal evaluating implanted left atrial appendage (LAA) occlusion devices by cardiac computed tomography angiography (cCTA) has never been investigated.

Authors: Michael Behnes, Ibrahim Akin, Benjamin Sartorius, Christian Fastner, Ibrahim El-Battrawy, Martin Borggrefe, Holger Haubenreisser, Mathias Meyer, Stefan O. Schoenberg and Thomas Henzler

Intraoperative 3D imaging in the treatment of elbow fractures - a retrospective analysis of indications, intraoperative revision rates, and implications in 36 cases

Three-dimensional (3D) imaging with a mobile C-arm has proven to be a valuable intraoperative tool in trauma surgery. However, little data is available concerning its use in the treatment of elbow fractures. T...

Authors: Marc Schnetzke, Julia Fuchs, Sven Y. Vetter, Nils Beisemann, Holger Keil, Paul-Alfred Grützner and Jochen Franke

Efficient quantitative assessment of facial paralysis using iris segmentation and active contour-based key points detection with hybrid classifier

Facial palsy or paralysis (FP) is a symptom that loses voluntary muscles movement in one side of the human face, which could be very devastating in the part of the patients. Traditional methods are solely depe...

Authors: Jocelyn Barbosa, Kyubum Lee, Sunwon Lee, Bilal Lodhi, Jae-Gu Cho, Woo-Keun Seo and Jaewoo Kang

Cognitive tasks and cerebral blood flow through anterior cerebral arteries: a study via functional transcranial Doppler ultrasound recordings

Functional transcanial Doppler ultrasound (fTCD) is a convenient approach to examine cerebral blood flow velocity (CBFV) in major cerebral arteries.

Authors: Héloïse Bleton, Subashan Perera and Ervin Sejdić

Increased enhancement of the liver adjacent to the gallbladder seen with contrast ultrasound: comparison between acute cholecystitis and non-cholecystitis

This study was performed to evaluate the ability of contrast-enhanced ultrasonography (CEUS) with time-intensity curve analysis to demonstrate an increased enhancement of the liver parenchyma adjacent to the i...

Authors: Ryousuke Kawai, Jiro Hata, Noriaki Manabe, Hiroshi Imamura, Ai Iida, Nobuko Koyama and Hiroaki Kusunoki

BMC Medical Imaging reviewer acknowledgement 2015

The editors of BMC Medical Imaging would like to thank all our reviewers who have contributed to the journal in Volume 15 (2015).

Authors: Clare Partridge

Automatic segmentation of myocardium at risk from contrast enhanced SSFP CMR: validation against expert readers and SPECT

Efficacy of reperfusion therapy can be assessed as myocardial salvage index (MSI) by determining the size of myocardium at risk (MaR) and myocardial infarction (MI), (MSI = 1-MI/MaR). Cardiovascular magnetic r...

Authors: Jane Tufvesson, Marcus Carlsson, Anthony H. Aletras, Henrik Engblom, Jean-François Deux, Sasha Koul, Peder Sörensson, John Pernow, Dan Atar, David Erlinge, Håkan Arheden and Einar Heiberg

Whole body cardiovascular magnetic resonance imaging to stratify symptomatic and asymptomatic atherosclerotic burden in patients with isolated cardiovascular disease

The aim of this study was to use whole body cardiovascular magnetic resonance imaging (WB CVMR) to assess the heart and arterial network in a single examination, so as to describe the burden of atherosclerosis...

Authors: Jonathan R. Weir-McCall, Suzanne L. Duce, Stephen J. Gandy, Shona Z. Matthew, Patricia Martin, Deirdre B. Cassidy, Lynne McCormick, Jill J. F. Belch, Allan D. Struthers, Helen M. Colhoun and J. Graeme Houston

Correlation between degenerative spine disease and bone marrow density: a retrospective investigation

Spondylosis leads to an overestimation of bone mineral density (BMD) with dual-energy x-ray absorptiometry (DXA) but not with quantitative computed tomography (QCT). The correlation between degenerative change...

Authors: Astrid Ellen Grams, Rafael Rehwald, Alexander Bartsch, Sarah Honold, Christian Franz Freyschlag, Michael Knoflach, Elke Ruth Gizewski and Bernhard Glodny

Prostate cancer arising in ectopic prostatic tissue within the left seminal vesicle: a rare case diagnosed with multi-parametric magnetic resonance imaging and magnetic resonance imaging-transrectal ultrasound fusion biopsy

Benign ectopia of prostatic glandular tissue in the seminal vesicles is rare with only three prior cases reported in the literature. Prostate cancer, arising within prostatic ectopia in the seminal vesicles, h...

Authors: Alexander S. Somwaru, Deepu Alex and Atif Zaheer

Near-infrared operating lamp for intraoperative molecular imaging of a mediastinal tumor

Near-Infrared (NIR) intraoperative molecular imaging is a new diagnostic modality utilized during cancer surgery for the identification of tumors, metastases and lymph nodes. Surgeons typically use headlamps d...

Authors: Jane Keating, Ryan Judy, Andrew Newton and Sunil Singhal

Radiomics-based differentiation of lung disease models generated by polluted air based on X-ray computed tomography data

Lung diseases (resulting from air pollution) require a widely accessible method for risk estimation and early diagnosis to ensure proper and responsive treatment. Radiomics-based fractal dimension analysis of ...

Authors: Krisztián Szigeti, Tibor Szabó, Csaba Korom, Ilona Czibak, Ildikó Horváth, Dániel S. Veres, Zoltán Gyöngyi, Kinga Karlinger, Ralf Bergmann, Márta Pócsik, Ferenc Budán and Domokos Máthé

Preoperative axillary lymph node staging by ultrasound-guided cytology using a four-level sonographic score

The staging of axillary lymph nodes is critical to the management and prognosis of breast cancer, the most frequent cancer in females. Neoadjuvant therapy and lymph node dissection are recommended when maligna...

Authors: Caroline De Coninck, Jean-Christophe Noël, Rachel Boutemy and Philippe Simon

Head and neck paragangliomas: diffusion weighted and dynamic contrast enhanced magnetic resonance imaging characteristics

To determine the feature values of head and neck paragangliomas on diffusion-weighted imaging (DWI) and dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI).

Authors: Ying Yuan, Huimin Shi and Xiaofeng Tao

A sinogram denoising algorithm for low-dose computed tomography

From the viewpoint of the patients’ health, reducing the radiation dose in computed tomography (CT) is highly desirable. However, projection measurements acquired under low-dose conditions will contain much no...

Authors: Davood Karimi, Pierre Deman, Rabab Ward and Nancy Ford