Articles

An artificial neural networks approach for assessment treatment response in oncological patients using PET/CT images

Positron Emission Tomography – Computed Tomography (PET/CT) imaging is the basis for the evaluation of response-to-treatment of several oncological diseases. In practice, such evaluation is manually performed ...

Authors: Mariana A. Nogueira, Pedro H. Abreu, Pedro Martins, Penousal Machado, Hugo Duarte and João Santos

Three-dimensional comparison of intramuscular fat content between young and old adults

Fat infiltration within skeletal muscle is known as intramuscular fat (IMF), which increases with aging. Studies have assessed IMF content, using the mid-thigh as a representative location. However, three-dime...

Authors: Akito Yoshiko, Maya Hioki, Nana Kanehira, Kiyoshi Shimaoka, Teruhiko Koike, Hisataka Sakakibara, Yoshiharu Oshida and Hiroshi Akima

Developing a nomogram based on multiparametric magnetic resonance imaging for forecasting high-grade prostate cancer to reduce unnecessary biopsies within the prostate-specific antigen gray zone

Since 1980s the application of Prostate specific antigen (PSA) brought the revolution in prostate cancer diagnosis. However, it is important to underline that PSA is not the ideal screening tool due to its low...

Authors: Xiang-ke Niu, Jun Li, Susant Kumar Das, Yan Xiong, Chao-bing Yang and Tao Peng

Combination of IVIM-DWI and 3D-ASL for differentiating true progression from pseudoprogression of Glioblastoma multiforme after concurrent chemoradiotherapy: study protocol of a prospective diagnostic trial

Standard therapy for Glioblastoma multiforme (GBM) involves maximal safe tumor resection followed with radiotherapy and concurrent adjuvant temozolomide. About 20 to 30% patients undergoing their first post-ra...

Authors: Zhi-Cheng Liu, Lin-Feng Yan, Yu-Chuan Hu, Ying-Zhi Sun, Qiang Tian, Hai-Yan Nan, Ying Yu, Qian Sun, Wen Wang and Guang-Bin Cui

T2 relaxation time for intervertebral disc degeneration in patients with upper back pain: initial results on the clinical use of 3.0 Tesla MRI

Magnetic resonance imaging (MRI) is a useful non-invasive tool for evaluating abnormalities of intervertebral discs. However, there are few studies which applied functional MRI techniques to investigate degene...

Authors: Raoying Xie, linhui Ruan, Lei chen, Kai Zhou, Jiandong Yuan, Wei Ji, Guangjian Jing, Xiaojing Huang, Qinglei Shi and Chun Chen

Characteristics of incidentally found thyroid nodules in computed tomography: comparison with thyroid scintigraphy

In our daily experience, the differentiation between a cold and hot nodule is a very important factor for further clinical management of the patient.

Authors: Shahin Zandieh, Dina Muin, Reinhard Bernt, Karl Hittmair, Joerg Haller and Klaus Hergan

Computed tomography and magnetic resonance imaging of a plexiform angiomyxoid myofibroblastic tumor: a case report

Plexiform angiomyxoid myofibroblastic tumor (PAMT) is a very rare mesenchymal tumor of the stomach. Here we report a case of pathologically confirmed PAMT with an unique cyst formation.

Authors: Hiroyuki Akai, Shigeru Kiryu, Masaru Shinozaki, Yasunori Ohta, Yoshiyasu Nakano, Koichiro Yasaka and Kuni Ohtomo

Multi-contrast brain magnetic resonance image super-resolution using the local weight similarity

Low-resolution images may be acquired in magnetic resonance imaging (MRI) due to limited data acquisition time or other physical constraints, and their resolutions can be improved with super-resolution methods...

Authors: Hong Zheng, Xiaobo Qu, Zhengjian Bai, Yunsong Liu, Di Guo, Jiyang Dong, Xi Peng and Zhong Chen

CT characteristics of non-small cell lung cancer with epidermal growth factor receptor mutation: a systematic review and meta-analysis

To systematically investigate the relationship between CT morphological features and the presence of epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC).

Authors: Zenghui Cheng, Fei Shan, Yuesong Yang, Yuxin Shi and Zhiyong Zhang

Newly recognized cerebral infarctions on postmortem imaging: a report of three cases with systemic infectious disease

Postmortem imaging (PMI) refers to the imaging of cadavers by computed tomography (CT) and/or magnetic resonance imaging (MRI). Three cases of cerebral infarctions that were not found during life but were newl...

Authors: Sakon Noriki, Kazuyuki Kinoshita, Kunihiro Inai, Toyohiko Sakai, Hirohiko Kimura, Takahiro Yamauchi, Masayuki Iwano and Hironobu Naiki

A case report in cardiovascular magnetic resonance: the contrast agent matters in amyloid

Cardiac amyloidosis is a progressive but underdiagnosed and underappreciated cause of heart failure. In the last few years, cardiovascular magnetic resonance (CMR) has become the gold standard for non invasive...

Authors: Marianna Fontana, Thomas A. Treibel, Ana Martinez-Naharro, Stefania Rosmini, Raymond Y. Kwong, Julian D. Gillmore, Philip N. Hawkins and James C. Moon

Dimensionality reduction-based fusion approaches for imaging and non-imaging biomedical data: concepts, workflow, and use-cases

With a wide array of multi-modal, multi-protocol, and multi-scale biomedical data being routinely acquired for disease characterization, there is a pressing need for quantitative tools to combine these varied ...

Authors: Satish E. Viswanath, Pallavi Tiwari, George Lee and Anant Madabhushi

FDG PET using SUV_max for preoperative T-staging of esophageal squamous cell carcinoma with and without neoadjuvant chemoradiotherapy

Accurate T-staging is pivotal for predicting prognosis and selecting appropriate therapies for esophageal squamous cell carcinoma (ESCC). The diagnostic performance of fluorodeoxyglucose (FDG) positron emissio...

Authors: Yung-Cheng Huang, Hung-I Lu, Shun-Chen Huang, Chien-Chin Hsu, Nan-Tsing Chiu, Yu-Ming Wang, Yi-Chun Chiu and Shau-Hsuan Li

Skeleton-based cerebrovascular quantitative analysis

Cerebrovascular disease is the most common cause of death worldwide, with millions of deaths annually. Interest is increasing toward understanding the geometric factors that influence cerebrovascular diseases,...

Authors: Xingce Wang, Enhui Liu, Zhongke Wu, Feifei Zhai, Yi-Cheng Zhu, Wuyang Shui and Mingquan Zhou

Intra- and inter-observer reliability of a new standardized diagnostic method using SPECT/CT in patients with osteochondral lesions of the ankle joint

Single Photon Emission Computed Tomography-Computed Tomography (SPECT/CT) gains an important part of diagnostics in patients with osteochondral lesions (OCL). SPECT/CT is a hybrid imaging modality, which combi...

Authors: Geneviève Hassink, Enrique A. Testa, André Leumann, Thomas Hügle, Helmut Rasch and Michael T. Hirschmann

The 5th International Conference on Biomedical Engineering and Biotechnology (ICBEB 2016)

Authors: Shaoqing Wang, Xiancun Yang, Meixia Su, Qiang Liu, Tao Gong, Qi Mao, Shuguang Zhao, Fang Han, Keming Mao, Yixian Liu, Yanchun Zhu, Shuo Li, Jie Yang, Nan Fu, Shaode Yu, Rongmao Li…

Prevalence and location of the secondary mesiobuccal canal in 1,100 maxillary molars using cone beam computed tomography

Several articles have used cone beam computed tomography (CBCT) to study the morphology of the maxillary molars and to ascertain its ability to visualize the second mesiobuccal canal (MB2); however, its geomet...

Authors: Pablo Betancourt, Pablo Navarro, Gonzalo Muñoz and Ramón Fuentes

Chemical shift MR imaging in the lumbar vertebra: the effect of field strength, scanner vendors and flip angles in repeatability of signal intensity index measurement

To evaluate the reproducibility of signal intensity index (SII) measurements with MRI systems from different vendors and with different field strengths, and to test the effectiveness of flip angle.

Authors: Zebin Xiao, Jian Li, Chengqi Li, Yuyang Zhang, Dejun She and Dairong Cao

Comparison of coronary arterial lumen dimensions on angiography and plaque characteristics on optical coherence tomography images and their changes induced by statin

Coronary angiography (CAG) is widely used to assess lumen dimensions, and optical coherence tomography (OCT) is used to evaluate the characteristics of atherosclerotic plaque. This study was aimed to compare c...

Authors: Nana Dong, Zulong Xie, Wei Wang, Jiannan Dai, Meng Sun, Zhongyue Pu, Jinwei Tian and Bo Yu

Qualitative analysis of small (≤2 cm) regenerative nodules, dysplastic nodules and well-differentiated HCCs with gadoxetic acid MRI

The characterization of small lesions in cirrhotic patients is extremely difficult due to the overlap of imaging features among different entities in the step-way of the hepatocarcinogenesis. The aim of our st...

Authors: Michele Di Martino, Michele Anzidei, Fulvio Zaccagna, Luca Saba, Sandro Bosco, Massimo Rossi, Stefano Ginanni Corradini and Carlo Catalano

Variation in type and frequency of diagnostic imaging during trauma care across multiple time points by patient insurance type

Research has shown that uninsured patients receive fewer radiographic studies during trauma care, but less is known as to whether differences in care are present among other insurance groups or across differen...

Authors: Nathaniel Bell, Laura Repáraz, William R. Fry, R. Stephen Smith and Alejandro Luis

Kinematic analysis of diastolic function using the freely available software Echo E-waves – feasibility and reproducibility

Early diastolic left ventricular (LV) filling can be accurately described using the same methods used in classical mechanics to describe the motion of a loaded spring as it recoils, a validated method also ref...

Authors: Martin G. Sundqvist, Katrin Salman, Per Tornvall and Martin Ugander

Characterization of ten white matter tracts in a representative sample of Cuban population

The diffusion tensor imaging technique (DTI) combined with tractography methods, has achieved the tridimensional reconstruction of white matter tracts in the brain. It allows their characterization in vivo in ...

Authors: D. Góngora, M. Domínguez and M. A. Bobes

¹⁸F-FDG uptake in the stomach on screening PET/CT: value for predicting Helicobacter pylori infection and chronic atrophic gastritis

The aim of this study was to determine the value of ¹⁸F-FDG uptake on screening PET/CT images for the prediction of Helicobacter pylori (H. pylori) infection and chronic atrophic gastritis.

Authors: Shigeki Kobayashi, Mayumi Ogura, Naohisa Suzawa, Noriyuki Horiki, Masaki Katsurahara, Toru Ogura and Hajime Sakuma

Mapping breast tissue types by miniature radio-frequency near-field spectroscopy sensor in ex-vivo freshly excised specimens

Receiving real-time information on tissue properties while performing biopsy procedures has the potential of improving biopsy accuracy. The study goal was to test the ability of a miniature flexible Radio-Freq...

Authors: Zvi Kaufman, Haim Paran, Ilana Haas, Patricia Malinger, Tania Zehavi, Tamar Karni, Izhak Pappo, Judith Sandbank, Judith Diment and Tanir Allweis

The effect of intramuscular interferon beta-1a on spinal cord volume in relapsing-remitting multiple sclerosis

Spinal cord atrophy occurs early in multiple sclerosis (MS) and impacts disability. The therapeutic effect of interferon beta-1a (IFNβ-1a) on spinal cord atrophy in patients with relapsing-remitting (RR) MS ha...

Authors: Sheena L. Dupuy, Fariha Khalid, Brian C. Healy, Sonya Bakshi, Mohit Neema, Shahamat Tauhid and Rohit Bakshi

A deformable template method for describing and averaging the anatomical variation of the human nasal cavity

Understanding airflow through human airways is of importance in drug delivery and development of assisted breathing methods. In this work, we focus on development of a new method to obtain an averaged upper ai...

Authors: Alireza Nejati, Natalia Kabaliuk, Mark C. Jermy and John E. Cater

How to assess intra- and inter-observer agreement with quantitative PET using variance component analysis: a proposal for standardisation

Quantitative measurement procedures need to be accurate and precise to justify their clinical use. Precision reflects deviation of groups of measurement from another, often expressed as proportions of agreemen...

Authors: Oke Gerke, Mie Holm Vilstrup, Eivind Antonsen Segtnan, Ulrich Halekoh and Poul Flemming Høilund-Carlsen

Differences in sex distribution, anatomic location and MR imaging appearance of pediatric compared to adult chordomas

Chordomas are rare malignancies that primarily affect adults, but also rarely affect pediatric patients. We compared the imaging appearance, demographic and anatomic distributions of adult and pediatric chordo...

Authors: Ronnie Sebro, Thomas DeLaney, Francis Hornicek, Joseph Schwab, Edwin Choy, G. Petur Nielsen and Daniel I. Rosenthal

Applying a computer-aided scheme to detect a new radiographic image marker for prediction of chemotherapy outcome

To investigate the feasibility of automated segmentation of visceral and subcutaneous fat areas from computed tomography (CT) images of ovarian cancer patients and applying the computed adiposity-related image...

Authors: Yunzhi Wang, Yuchen Qiu, Theresa Thai, Kathleen Moore, Hong Liu and Bin Zheng

Sparse reconstruction of compressive sensing MRI using cross-domain stochastically fully connected conditional random fields

Magnetic Resonance Imaging (MRI) is a crucial medical imaging technology for the screening and diagnosis of frequently occurring cancers. However, image quality may suffer from long acquisition times for MRIs ...

Authors: Edward Li, Farzad Khalvati, Mohammad Javad Shafiee, Masoom A. Haider and Alexander Wong

Multimodal MRI for early diabetic mild cognitive impairment: study protocol of a prospective diagnostic trial

Type 2 diabetes mellitus (T2DM) is a risk factor for dementia. Mild cognitive impairment (MCI), an intermediary state between normal cognition and dementia, often occurs during the prodromal diabetic stage, ma...

Authors: Ying Yu, Qian Sun, Lin-Feng Yan, Yu-Chuan Hu, Hai-Yan Nan, Yang Yang, Zhi-Cheng Liu, Wen Wang and Guang-Bin Cui

The effect of patient anxiety and depression on motion during myocardial perfusion SPECT imaging

Patient motion during myocardial perfusion SPECT imaging (MPI) may be triggered by a patient’s physical and/or psychological discomfort. The aim of this study was to investigate the impact of state anxiety (pa...

Authors: Vassiliki Lyra, Maria Kallergi, Emmanouil Rizos, Georgios Lamprakopoulos and Sofia N. Chatziioannou

Color radiography in lung nodule detection and characterization: comparison with conventional gray scale radiography

To compare the capability of lung nodule detection and characterization between dual-energy radiography with color-representation (DCR) and conventional gray scale chest radiography (GSR).

Authors: Inyoung Song, Jeong Geun Yi, Jeong Hee Park, Kyung Soo Lee and Myung Jin Chung

Evaluation of energy spectrum CT for the measurement of thyroid iodine content

This study aims to provide a reference for the diagnosis of iodine deficiency disorder by evaluating the normal thyroid iodine content by energy spectrum computed tomography (CT) and calculating the iodine con...

Authors: Weiguang Shao, Jingang Liu and Dianmei Liu

Validation of T1 and T2 algorithms for quantitative MRI: performance by a vendor-independent software

Determination of the relaxation time constants T1 and T2 with quantitative magnetic resonance imaging is increasingly used for both research and clinical practice. Recently, groups have been formed within the ...

Authors: Sebastian Bidhult, George Kantasis, Anthony H. Aletras, Håkan Arheden, Einar Heiberg and Erik Hedström

Counter-clockwise vortical blood flow in the main pulmonary artery in a patient with patent ductus arteriosus with pulmonary arterial hypertension: a cardiac magnetic resonance imaging case report

In patients with pulmonary hypertension (PH), duration of vortical blood flow along the main pulmonary artery enables estimation of the mean pulmonary arterial pressure (mPAP) non-invasively. It remains to dat...

Authors: Gert Reiter, Ursula Reiter, Gabor Kovacs, Gabriel Adelsmayr, Andreas Greiser, Aurelien F. Stalder, Horst Olschewski and Michael Fuchsjäger

Reliability of radiographic measurements for acute distal radius fractures

The management of distal radial fractures is guided by the interpretation of radiographic findings. The aim of this investigation was to determine the intra- and inter-observer reliability of eight traditional...

Authors: Narelle J. Watson, Saeed Asadollahi, Frank Parrish, Jacqueline Ridgway, Phong Tran and Jennifer L. Keating

Evaluation of dynamic infrared thermography as an alternative to CT angiography for perforator mapping in breast reconstruction: a clinical study

The current gold standard for preoperative perforator mapping in breast reconstruction with a DIEP flap is CT angiography (CTA). Dynamic infrared thermography (DIRT) is an imaging method that does not require ...

Authors: Sven Weum, James B. Mercer and Louis de Weerd

Impact of region-of-interest method on quantitative analysis of DTI data in the optic tracts

To extract DTI parameters from a specific structure, a region of interest (ROI) must be defined. ROI selection in small structures is challenging; the final measurement results could be affected due to the sig...

Authors: Ylva Lilja, Oscar Gustafsson, Maria Ljungberg, Daniel Nilsson and Göran Starck

Radiation dosimetry of 18F-FDG PET/CT: incorporating exam-specific parameters in dose estimates

Whole body fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) is the standard of care in oncologic diagnosis and staging, and patient radiation dose must be well understoo...

Authors: Brian Quinn, Zak Dauer, Neeta Pandit-Taskar, Heiko Schoder and Lawrence T. Dauer

A statistical shape modelling framework to extract 3D shape biomarkers from medical imaging data: assessing arch morphology of repaired coarctation of the aorta

Medical image analysis in clinical practice is commonly carried out on 2D image data, without fully exploiting the detailed 3D anatomical information that is provided by modern non-invasive medical imaging tec...

Authors: Jan L. Bruse, Kristin McLeod, Giovanni Biglino, Hopewell N. Ntsinjana, Claudio Capelli, Tain-Yen Hsia, Maxime Sermesant, Xavier Pennec, Andrew M. Taylor and Silvia Schievano

Osteoblastic lesion screening with an advanced post-processing package enabling in-plane rib reading in CT-images

To evaluate screening and diagnostic accuracy for the detection of osteoblastic rib lesions using an advanced post-processing package enabling in-plane rib reading in CT-images.

Authors: Hannes Seuss, Peter Dankerl, Alexander Cavallaro, Michael Uder and Matthias Hammon

Development of a morphology-based modeling technique for tracking solid-body displacements: examining the reliability of a potential MRI-only approach for joint kinematics assessment

Single or biplanar video radiography and Roentgen stereophotogrammetry (RSA) techniques used for the assessment of in-vivo joint kinematics involves application of ionizing radiation, which is a limitation for cl...

Authors: Niladri K. Mahato, Stephane Montuelle, John Cotton, Susan Williams, James Thomas and Brian Clark

Magnetic resonance enterography changes after antibody to tumor necrosis factor (anti-TNF) alpha therapy in Crohn’s disease: correlation with SES-CD and clinical-biological markers

In recent years, the use of MRI in patients with Crohn’s disease (CD) has increased. However, few data are available on how MRI parameters of active disease change during treatment with anti-TNF and whether th...

Authors: Luca Pio Stoppino, Nicola Della Valle, Stefania Rizzi, Elsa Cleopazzo, Annarita Centola, Donatello Iamele, Christos Bristogiannis, Giuseppe Stoppino, Roberta Vinci and Luca Macarini

A case of intra-articular ganglion cysts of the knee joint: correlation between arthroscopic and magnetic resonance imaging

Intra-articular ganglion cysts of the knee are rare. Here we report a case of an arthroscopically confirmed ganglion cyst arising from the posterior cruciate ligament (PCL) along with preoperative magnetic res...

Authors: Sayaka Kodaira, Takahito Nakajima, Ryosuke Takahashi, Shingo Moriya, Tomoyuki Nakagawa, Hidenori Ohtake and Yoshito Tsushima

Current T₁ and T₂ mapping techniques applied with simple thresholds cannot discriminate acute from chronic myocadial infarction on an individual patient basis: a pilot study

Studying T₁- and T₂-mapping for discrimination of acute from chronic myocardial infarction (AMI, CMI).

Authors: Florian von Knobelsdorff-Brenkenhoff, Marcel Prothmann, Matthias A. Dieringer, Ralf Wassmuth, André Rudolph, Wolfgang Utz, Julius Traber, Andreas Greiser, Thoralf Niendorf and Jeanette Schulz-Menger

Quantification of maceration changes using post mortem MRI in fetuses

Post mortem imaging is playing an increasingly important role in perinatal autopsy, and correct interpretation of imaging changes is paramount. This is particularly important following intra-uterine fetal deat...

Authors: P. Montaldo, S. Addison, V. Oliveira, P. J. Lally, A. M. Taylor, N. J. Sebire, S. Thayyil and O. J. Arthurs

Erratum to: prostate cancer arising in ectopic prostatic tissue within the left seminal vesicle: a rare case diagnosed with multi-parametric magnetic resonance imaging and magnetic resonance imaging-transrectal ultrasound fusion biopsy

Authors: Alexander S. Somwaru, Deepu Alex and Atif Zaheer

Anisakiasis mimics cancer recurrence: two cases of extragastrointestinal anisakiasis suspected to be recurrence of gynecological cancer on PET-CT and molecular biological investigation

We report two cases of anisakiasis lesions that were initially suspected to be recurrence of gynecological cancer by positron emission tomography-computed tomography (PET-CT). Both cases were extragastrointest...

Authors: Yuya Nogami, Yoko Fujii-Nishimura, Kouji Banno, Atsushi Suzuki, Nobuyuki Susumu, Taizo Hibi, Koji Murakami, Taketo Yamada, Hiromu Sugiyama, Yasuyuki Morishima and Daisuke Aoki