Articles

Development of a morphology-based modeling technique for tracking solid-body displacements: examining the reliability of a potential MRI-only approach for joint kinematics assessment

Single or biplanar video radiography and Roentgen stereophotogrammetry (RSA) techniques used for the assessment of in-vivo joint kinematics involves application of ionizing radiation, which is a limitation for cl...

Authors: Niladri K. Mahato, Stephane Montuelle, John Cotton, Susan Williams, James Thomas and Brian Clark

Magnetic resonance enterography changes after antibody to tumor necrosis factor (anti-TNF) alpha therapy in Crohn’s disease: correlation with SES-CD and clinical-biological markers

In recent years, the use of MRI in patients with Crohn’s disease (CD) has increased. However, few data are available on how MRI parameters of active disease change during treatment with anti-TNF and whether th...

Authors: Luca Pio Stoppino, Nicola Della Valle, Stefania Rizzi, Elsa Cleopazzo, Annarita Centola, Donatello Iamele, Christos Bristogiannis, Giuseppe Stoppino, Roberta Vinci and Luca Macarini

A case of intra-articular ganglion cysts of the knee joint: correlation between arthroscopic and magnetic resonance imaging

Intra-articular ganglion cysts of the knee are rare. Here we report a case of an arthroscopically confirmed ganglion cyst arising from the posterior cruciate ligament (PCL) along with preoperative magnetic res...

Authors: Sayaka Kodaira, Takahito Nakajima, Ryosuke Takahashi, Shingo Moriya, Tomoyuki Nakagawa, Hidenori Ohtake and Yoshito Tsushima

Current T₁ and T₂ mapping techniques applied with simple thresholds cannot discriminate acute from chronic myocadial infarction on an individual patient basis: a pilot study

Studying T₁- and T₂-mapping for discrimination of acute from chronic myocardial infarction (AMI, CMI).

Authors: Florian von Knobelsdorff-Brenkenhoff, Marcel Prothmann, Matthias A. Dieringer, Ralf Wassmuth, André Rudolph, Wolfgang Utz, Julius Traber, Andreas Greiser, Thoralf Niendorf and Jeanette Schulz-Menger

Quantification of maceration changes using post mortem MRI in fetuses

Post mortem imaging is playing an increasingly important role in perinatal autopsy, and correct interpretation of imaging changes is paramount. This is particularly important following intra-uterine fetal deat...

Authors: P. Montaldo, S. Addison, V. Oliveira, P. J. Lally, A. M. Taylor, N. J. Sebire, S. Thayyil and O. J. Arthurs

Practical one-dimensional measurements of age-related brain atrophy are validated by 3-dimensional values and clinical outcomes: a retrospective study

Age-related brain atrophy has been represented by simple 1-dimensional (1-D) measurements on computed tomography (CT) for several decades and, more recently, with 3-dimensional (3-D) analysis, using brain volu...

Authors: C. Michael Dunham, Albert J. Cook II, Alaina M. Paparodis and Gregory S. Huang

Anisakiasis mimics cancer recurrence: two cases of extragastrointestinal anisakiasis suspected to be recurrence of gynecological cancer on PET-CT and molecular biological investigation

We report two cases of anisakiasis lesions that were initially suspected to be recurrence of gynecological cancer by positron emission tomography-computed tomography (PET-CT). Both cases were extragastrointest...

Authors: Yuya Nogami, Yoko Fujii-Nishimura, Kouji Banno, Atsushi Suzuki, Nobuyuki Susumu, Taizo Hibi, Koji Murakami, Taketo Yamada, Hiromu Sugiyama, Yasuyuki Morishima and Daisuke Aoki

Erratum to: prostate cancer arising in ectopic prostatic tissue within the left seminal vesicle: a rare case diagnosed with multi-parametric magnetic resonance imaging and magnetic resonance imaging-transrectal ultrasound fusion biopsy

Authors: Alexander S. Somwaru, Deepu Alex and Atif Zaheer

3D rotational fluoroscopy for intraoperative clip control in patients with intracranial aneurysms – assessment of feasibility and image quality

Mobile 3D fluoroscopes have become increasingly available in neurosurgical operating rooms. In this series, the image quality and value of intraoperative 3D fluoroscopy with intravenous contrast agent for the ...

Authors: Thomas Westermaier, Thomas Linsenmann, György A. Homola, Mario Loehr, Christian Stetter, Nadine Willner, Ralf-Ingo Ernestus, Laszlo Solymosi and Giles H. Vince

Clinical value of endoluminal ultrasonography in the diagnosis of rectovaginal fistula

Rectovaginal fistula (RVF) refers to a pathological passage between the rectum and vagina, which is a public health challenge. This study was aimed to explore the clinical value of endoluminal biplane ultrason...

Authors: Hao-Qiang Yin, Chen Wang, Xin Peng, Fang Xu, Ya-Juan Ren, Yong-Qing Chao, Jin-Gen Lu, Song Wang and Hu-Sheng Xiao

Pelvic retroperitoneal pleomorphic hyalinizing angiectatic tumor (PHAT) of soft tissue: a case report

Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare soft tissue tumor of low malignant potential, which most often arises in the lower extremities. Lesions occurred in other anatomic locations have been...

Authors: Zhi-gang Chu, Meng-qi Liu, Zhi-yu Zhu, Fa-jin Lv and Yu Ouyang

The correlation between radiographic and pathologic grading of lumbar facet joint degeneration

Before performing spine non-fusion surgery that retains the facet joints, choosing an accurate radiographic method to evaluate the degree of facet joint degeneration is extremely important. Therefore, the obje...

Authors: Xin Zhou, Yuan Liu, Song Zhou, Xiao-Xing Fu, Xiao-Long Yu, Chang-Lin Fu, Bin Zhang and Min Dai

Phase-contrast MRI volume flow – a comparison of breath held and navigator based acquisitions

Magnetic Resonance Imaging (MRI) 2D phase-contrast flow measurement has been regarded as the gold standard in blood flow measurements and can be performed with free breathing or breath held techniques. We hypo...

Authors: Charlotta Andersson, Johan Kihlberg, Tino Ebbers, Lena Lindström, Carl-Johan Carlhäll and Jan E. Engvall

- LAA Occluder View for post-implantation Evaluation (LOVE) - standardized imaging proposal evaluating implanted left atrial appendage occlusion devices by cardiac computed tomography

A standardized imaging proposal evaluating implanted left atrial appendage (LAA) occlusion devices by cardiac computed tomography angiography (cCTA) has never been investigated.

Authors: Michael Behnes, Ibrahim Akin, Benjamin Sartorius, Christian Fastner, Ibrahim El-Battrawy, Martin Borggrefe, Holger Haubenreisser, Mathias Meyer, Stefan O. Schoenberg and Thomas Henzler

Intraoperative 3D imaging in the treatment of elbow fractures - a retrospective analysis of indications, intraoperative revision rates, and implications in 36 cases

Three-dimensional (3D) imaging with a mobile C-arm has proven to be a valuable intraoperative tool in trauma surgery. However, little data is available concerning its use in the treatment of elbow fractures. T...

Authors: Marc Schnetzke, Julia Fuchs, Sven Y. Vetter, Nils Beisemann, Holger Keil, Paul-Alfred Grützner and Jochen Franke

Efficient quantitative assessment of facial paralysis using iris segmentation and active contour-based key points detection with hybrid classifier

Facial palsy or paralysis (FP) is a symptom that loses voluntary muscles movement in one side of the human face, which could be very devastating in the part of the patients. Traditional methods are solely depe...

Authors: Jocelyn Barbosa, Kyubum Lee, Sunwon Lee, Bilal Lodhi, Jae-Gu Cho, Woo-Keun Seo and Jaewoo Kang

Cognitive tasks and cerebral blood flow through anterior cerebral arteries: a study via functional transcranial Doppler ultrasound recordings

Functional transcanial Doppler ultrasound (fTCD) is a convenient approach to examine cerebral blood flow velocity (CBFV) in major cerebral arteries.

Authors: Héloïse Bleton, Subashan Perera and Ervin Sejdić

Increased enhancement of the liver adjacent to the gallbladder seen with contrast ultrasound: comparison between acute cholecystitis and non-cholecystitis

This study was performed to evaluate the ability of contrast-enhanced ultrasonography (CEUS) with time-intensity curve analysis to demonstrate an increased enhancement of the liver parenchyma adjacent to the i...

Authors: Ryousuke Kawai, Jiro Hata, Noriaki Manabe, Hiroshi Imamura, Ai Iida, Nobuko Koyama and Hiroaki Kusunoki

BMC Medical Imaging reviewer acknowledgement 2015

The editors of BMC Medical Imaging would like to thank all our reviewers who have contributed to the journal in Volume 15 (2015).

Authors: Clare Partridge

Automatic segmentation of myocardium at risk from contrast enhanced SSFP CMR: validation against expert readers and SPECT

Efficacy of reperfusion therapy can be assessed as myocardial salvage index (MSI) by determining the size of myocardium at risk (MaR) and myocardial infarction (MI), (MSI = 1-MI/MaR). Cardiovascular magnetic r...

Authors: Jane Tufvesson, Marcus Carlsson, Anthony H. Aletras, Henrik Engblom, Jean-François Deux, Sasha Koul, Peder Sörensson, John Pernow, Dan Atar, David Erlinge, Håkan Arheden and Einar Heiberg

Whole body cardiovascular magnetic resonance imaging to stratify symptomatic and asymptomatic atherosclerotic burden in patients with isolated cardiovascular disease

The aim of this study was to use whole body cardiovascular magnetic resonance imaging (WB CVMR) to assess the heart and arterial network in a single examination, so as to describe the burden of atherosclerosis...

Authors: Jonathan R. Weir-McCall, Suzanne L. Duce, Stephen J. Gandy, Shona Z. Matthew, Patricia Martin, Deirdre B. Cassidy, Lynne McCormick, Jill J. F. Belch, Allan D. Struthers, Helen M. Colhoun and J. Graeme Houston

Correlation between degenerative spine disease and bone marrow density: a retrospective investigation

Spondylosis leads to an overestimation of bone mineral density (BMD) with dual-energy x-ray absorptiometry (DXA) but not with quantitative computed tomography (QCT). The correlation between degenerative change...

Authors: Astrid Ellen Grams, Rafael Rehwald, Alexander Bartsch, Sarah Honold, Christian Franz Freyschlag, Michael Knoflach, Elke Ruth Gizewski and Bernhard Glodny

Prostate cancer arising in ectopic prostatic tissue within the left seminal vesicle: a rare case diagnosed with multi-parametric magnetic resonance imaging and magnetic resonance imaging-transrectal ultrasound fusion biopsy

Benign ectopia of prostatic glandular tissue in the seminal vesicles is rare with only three prior cases reported in the literature. Prostate cancer, arising within prostatic ectopia in the seminal vesicles, h...

Authors: Alexander S. Somwaru, Deepu Alex and Atif Zaheer

Near-infrared operating lamp for intraoperative molecular imaging of a mediastinal tumor

Near-Infrared (NIR) intraoperative molecular imaging is a new diagnostic modality utilized during cancer surgery for the identification of tumors, metastases and lymph nodes. Surgeons typically use headlamps d...

Authors: Jane Keating, Ryan Judy, Andrew Newton and Sunil Singhal

Radiomics-based differentiation of lung disease models generated by polluted air based on X-ray computed tomography data

Lung diseases (resulting from air pollution) require a widely accessible method for risk estimation and early diagnosis to ensure proper and responsive treatment. Radiomics-based fractal dimension analysis of ...

Authors: Krisztián Szigeti, Tibor Szabó, Csaba Korom, Ilona Czibak, Ildikó Horváth, Dániel S. Veres, Zoltán Gyöngyi, Kinga Karlinger, Ralf Bergmann, Márta Pócsik, Ferenc Budán and Domokos Máthé

Preoperative axillary lymph node staging by ultrasound-guided cytology using a four-level sonographic score

The staging of axillary lymph nodes is critical to the management and prognosis of breast cancer, the most frequent cancer in females. Neoadjuvant therapy and lymph node dissection are recommended when maligna...

Authors: Caroline De Coninck, Jean-Christophe Noël, Rachel Boutemy and Philippe Simon

Head and neck paragangliomas: diffusion weighted and dynamic contrast enhanced magnetic resonance imaging characteristics

To determine the feature values of head and neck paragangliomas on diffusion-weighted imaging (DWI) and dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI).

Authors: Ying Yuan, Huimin Shi and Xiaofeng Tao

A sinogram denoising algorithm for low-dose computed tomography

From the viewpoint of the patients’ health, reducing the radiation dose in computed tomography (CT) is highly desirable. However, projection measurements acquired under low-dose conditions will contain much no...

Authors: Davood Karimi, Pierre Deman, Rabab Ward and Nancy Ford

A comparison of the quality of image acquisition between the incident dark field and sidestream dark field video-microscopes

The ‘Cytocam’ is a third generation video-microscope, which enables real time visualisation of the in vivo microcirculation. Based upon the principle of incident dark field (IDF) illumination, this hand held comp...

Authors: Edward Gilbert-Kawai, Jonny Coppel, Vassiliki Bountziouka, Can Ince and Daniel Martin

Three-dimensional reconstruction of coronary arteries and plaque morphology using CT angiography – comparison and registration with IVUS

The aim of this study is to present a new methodology for three-dimensional (3D) reconstruction of coronary arteries and plaque morphology using Computed Tomography Angiography (CTA).

Authors: Lambros Athanasiou, George Rigas, Antonis I. Sakellarios, Themis P. Exarchos, Panagiotis K. Siogkas, Christos V. Bourantas, Hector M. Garcia-Garcia, Pedro A. Lemos, Breno A. Falcao, Lampros K. Michalis, Oberdan Parodi, Federico Vozzi and Dimitrios I. Fotiadis

Paraneoplastic limbic encephalitis with associated hypothalamitis mimicking a hyperdense hypothalamic tumor: a case report

Paraneoplastic limbic encephalitis is an uncommon association of common malignancies such as small cell lung carcinoma, testicular teratoma, and breast carcinoma. The nonspecific nature of the clinical present...

Authors: Vipula R. Bataduwaarachchi and Nirmali Tissera

A semi-automated measuring system of brain diffusion and perfusion magnetic resonance imaging abnormalities in patients with multiple sclerosis based on the integration of coregistration and tissue segmentation procedures

Diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) abnormalities in patients with multiple sclerosis (MS) are currently measured by a complex combination of separate procedures. Therefore, t...

Authors: Alfredo Revenaz, Massimiliano Ruggeri, Marcella Laganà, Niels Bergsland, Elisabetta Groppo, Marco Rovaris and Enrico Fainardi

An open source software for analysis of dynamic contrast enhanced magnetic resonance images: UMMPerfusion revisited

Perfusion imaging has become an important image based tool to derive the physiological information in various applications, like tumor diagnostics and therapy, stroke, (cardio-) vascular diseases, or functiona...

Authors: Frank G. Zöllner, Markus Daab, Steven P. Sourbron, Lothar R. Schad, Stefan O. Schoenberg and Gerald Weisser

The use of matrigel has no influence on tumor development or PET imaging in FaDu human head and neck cancer xenografts

In preclinical research Matrixgel^TM Basement Membrane Matrix (MG) is used frequently for the establishment of syngeneic and xenograft cancer models. Limited information on its influence on parameters including; t...

Authors: Frederikke P. Fliedner, Anders E. Hansen, Jesper T. Jørgensen and Andreas Kjær

Classification of fibroglandular tissue distribution in the breast based on radiotherapy planning CT

Accurate segmentation of breast tissues is required for a number of applications such as model based deformable registration in breast radiotherapy. The accuracy of breast tissue segmentation is affected by th...

Authors: Prabhjot Juneja, Philip Evans, David Windridge and Emma Harris

Illegal intra-corporeal packets: can dual energy CT be used for the evaluation of cocaine concentration? A cross sectional study

The recent implementation of the dual energy technology on CT-scanners has opened new perspectives in tissue and material characterization. This study aims to evaluate whether dual energy CT can be used to ass...

Authors: Alexandra Platon, Minerva Becker, Christoph D. Becker, Eric Lock, Hans Wolff, Thomas Perneger and Pierre-Alexandre Poletti

Comparison of three ¹⁸F-labeled carboxylic acids with ¹⁸F-FDG of the differentiation tumor from inflammation in model mice

The aim of this study was to compare the properties and feasibility of the glucose analog, 2-¹⁸F-fluoro-2-deoxy-D-glucose (¹⁸F-FDG), three short ¹⁸F-labeled carboxylic acids, ¹⁸F-fluoroacetate (¹⁸F-FAC), 2-¹⁸F-fl...

Authors: Hongliang Wang, Ganghua Tang, Kongzhen Hu, Tingting Huang, Xiang Liang, Zhifang Wu and Sijin Li

Differentiation of sarcoidosis-lymphoma syndrome lesions: a case report on the use of two different positron emission tomography tracers

Sarcoidosis–lymphoma syndrome (SLS) is a rare disease in which both entities coexist. We aimed to study the role of ¹⁸F-fluorodeoxyglucose (FDG) and L–[3-¹⁸F] α-methyltyrosine (FAMT) positron emission tomography ...

Authors: Ryan Yudistiro, Yukiko Arisaka, Azusa Tokue and Takahito Nakajima

A chest radiograph scoring system in patients with severe acute respiratory infection: a validation study

The term severe acute respiratory infection (SARI) encompasses a heterogeneous group of respiratory illnesses. Grading the severity of SARI is currently reliant on indirect disease severity measures such as re...

Authors: Emma Taylor, Kathryn Haven, Peter Reed, Ange Bissielo, Dave Harvey, Colin McArthur, Cameron Bringans, Simone Freundlich, R. Joan H. Ingram, David Perry, Francessa Wilson, David Milne, Lucy Modahl, Q. Sue Huang, Diane Gross, Marc-Alain Widdowson…

Combined PET/CT-perfusion in patients with head and neck cancers might predict failure after radio-chemotherapy: a proof of concept study

[18F]FDG-PET/CT imaging is broadly used in head and neck cancer (HNSCC) patients. CT perfusion (CTP) is known to provide information about angiogenesis and blood-flow characteristics in tumors. The aim of this...

Authors: Carsten Pietsch, Felipe de Galiza Barbosa, Martin W. Hüllner, Daniel T. Schmid, Stephan K. Haerle, Gerhard F. Huber, Gabriela Studer, Thomas F. Hany and Patrick Veit-Haibach

New quantitative classification of the anatomical relationship between impacted third molars and the inferior alveolar nerve

Before extracting impacted lower third molars, dentists must first identify the spatial relationship between the inferior alveolar nerve (IAN) and an impacted lower third molar to prevent nerve injury from the...

Authors: Wei-Quan Wang, Michael Y. C. Chen, Heng-Li Huang, Lih-Jyh Fuh, Ming-Tzu Tsai and Jui-Ting Hsu

Comparison of Acoustic Structure Quantification (ASQ), shearwave elastography and histology in patients with diffuse hepatopathies

Objective of the study was to evaluate the diagnostic value of novel ultrasonographic modalities in comparison with simultaneously performed liver biopsy.

Authors: Jan Keller, Tanja Eva-Maria Kaltenbach, Mark Martin Haenle, Suemeyra Oeztuerk, Tilmann Graeter, Richard Andrew Mason, Thomas Seufferlein and Wolfgang Kratzer

Diagnostic imaging capabilities of the Ocelot -Optical Coherence Tomography System, ex-vivo evaluation and clinical relevance

Optical coherence tomography (OCT) is a high-resolution sub-surface imaging modality using near-infrared light to provide accurate and high contrast intra-vascular images. This enables accurate assessment of d...

Authors: Suhail Dohad, John Shao, Ian Cawich, Manish Kankaria and Arjun Desai

Prospective, randomized comparison of gadopentetate and gadobutrol to assess chronic myocardial infarction applying cardiovascular magnetic resonance

We hypothesized that the contrast medium gadobutrol is not inferior compared to Gd-DTPA in identifying and quantifying ischemic late gadolinium enhancement (LGE), even by using a lower dose.

Authors: Andre Rudolph, Daniel Messroghli, Florian von Knobelsdorff-Brenkenhoff, Julius Traber, Johannes Schüler, Ralf Wassmuth and Jeanette Schulz-Menger

A pilot study using low-dose Spectral CT and ASIR (Adaptive Statistical Iterative Reconstruction) algorithm to diagnose solitary pulmonary nodules

Lung cancer is the most common cancer which has the highest mortality rate. With the development of computed tomography (CT) techniques, the case detection rates of solitary pulmonary nodules (SPN) has constan...

Authors: Huijuan Xiao, Yihe Liu, Hongna Tan, Pan Liang, Bo Wang, Lei Su, Suya Wang and Jianbo Gao

Osseous vitality in single photon emission computed tomography/computed tomography (SPECT/CT) after balloon tibioplasty of the tibial plateau: a case series

The minimally invasive, balloon-assisted reduction and cement-augmented internal fixation of the tibial plateau is an innovative surgical procedure for tibial plateau fractures. The close proximity of balloons...

Authors: Thorsten Jentzsch, Yannick Fritz, Patrick Veit-Haibach, Jürgen Schmitt, Kai Sprengel and Clément M. L. Werner

Automatic detection of abnormalities in mammograms

In recent years, an increased interest has been seen in the area of medical image processing and, as a consequence, Computer Aided Diagnostic (CAD) systems. The basic purpose of CAD systems is to assist doctor...

Authors: Zobia Suhail, Mansoor Sarwar and Kashif Murtaza

Improved R2* liver iron concentration assessment using a novel fuzzy c-mean clustering scheme

In thalassemia patients, R2* liver iron concentration (LIC) measurement is a common clinical tool for assessing iron overload and for determining necessary chelator dose and evaluating its efficacy. Despite th...

Authors: Pairash Saiviroonporn, Vip Viprakasit and Rungroj Krittayaphong

Vision-based markerless registration using stereo vision and an augmented reality surgical navigation system: a pilot study

This study evaluated the use of an augmented reality navigation system that provides a markerless registration system using stereo vision in oral and maxillofacial surgery.

Authors: Hideyuki Suenaga, Huy Hoang Tran, Hongen Liao, Ken Masamune, Takeyoshi Dohi, Kazuto Hoshi and Tsuyoshi Takato

Automated lesion detection on MRI scans using combined unsupervised and supervised methods

Accurate and precise detection of brain lesions on MR images (MRI) is paramount for accurately relating lesion location to impaired behavior. In this paper, we present a novel method to automatically detect br...

Authors: Dazhou Guo, Julius Fridriksson, Paul Fillmore, Christopher Rorden, Hongkai Yu, Kang Zheng and Song Wang