Articles

Non-rigid image registration of 4D-MRI data for improved delineation of moving tumors

To increase the image quality of end-expiratory and end-inspiratory phases of retrospective respiratory self-gated 4D MRI data sets using non-rigid image registration for improved target delineation of moving ...

Authors: Stefan Weick, Kathrin Breuer, Anne Richter, Florian Exner, Serge-Peer Ströhle, Paul Lutyj, Jörg Tamihardja, Simon Veldhoen, Michael Flentje and Bülent Polat

Performance of TGSE BLADE DWI compared with RESOLVE DWI in the diagnosis of cholesteatoma

Based on its high resolution in soft tissue, MRI, especially diffusion-weighted imaging (DWI), is increasingly important in the evaluation of cholesteatoma. The purpose of this study was to evaluate the role o...

Authors: Yaru Sheng, Rujian Hong, Yan Sha, Zhongshuai Zhang, Kun Zhou and Caixia Fu

Cone beam computed tomographic analysis of the spatial limitation during mandibular arch distalization

In the literature, attempts are seldom made to quantify spatial limitation during mandibular arch distalization. This study aimed to investigate the spatial limitations associated with cortical contact with th...

Authors: Chia-Ling Chen, Chia-Hui Chen, Chin-Yun Pan, Hong-Po Chang, Ping-Ho Chen and Yu-Chuan Tseng

Improving the diagnosis of common parotid tumors via the combination of CT image biomarkers and clinical parameters

Our study aims to develop and validate diagnostic models of the common parotid tumors based on whole-volume CT textural image biomarkers (IBMs) in combination with clinical parameters at a single institution.

Authors: Dan Zhang, Xiaojiao Li, Liang Lv, Jiayi Yu, Chao Yang, Hua Xiong, Ruikun Liao, Bi Zhou, Xianlong Huang, Xiaoshuang Liu and Zhuoyue Tang

Weakly-supervised convolutional neural networks of renal tumor segmentation in abdominal CTA images

Renal cancer is one of the 10 most common cancers in human beings. The laparoscopic partial nephrectomy (LPN) is an effective way to treat renal cancer. Localization and delineation of the renal tumor from pre...

Authors: Guanyu Yang, Chuanxia Wang, Jian Yang, Yang Chen, Lijun Tang, Pengfei Shao, Jean-Louis Dillenseger, Huazhong Shu and Limin Luo

The utility of multi-stack alignment and 3D longitudinal image registration to assess bone remodeling in rheumatoid arthritis patients from second generation HR-pQCT scans

Medical imaging plays an important role in determining the progression of joint damage in rheumatoid arthritis (RA). High resolution peripheral quantitative computed tomography (HR-pQCT) is a sensitive tool ca...

Authors: Scott C. Brunet, Michael T. Kuczynski, Jennifer L. Bhatla, Sophie Lemay, Yves Pauchard, Peter Salat, Cheryl Barnabe and Sarah L. Manske

Imaging study of coronal structural matching of the distal radius in normal adults

As an important anatomical basis, coronal structural position matching of the distal radius has long been lacking in terms of a quantitative understanding, and such matching is correlated with the postoperativ...

Authors: Xin Zhang, Feng Yuan, Yong Yin and Jian Fan

Altered Achilles tendon morphology in individuals with chronic post-stroke hemiparesis: a case report

Individuals post-stroke walk slowly and with more effort, which puts them at higher risks for falls. The slow walking speed results from insufficient propulsive forces generated by the paretic leg. Current reh...

Authors: Jing Nong Liang and Kai-Yu Ho

Novel foetal echocardiographic image processing software (5D Heart) improves the display of key diagnostic elements in foetal echocardiography

To evaluate the clinical value of foetal intelligent navigation echocardiography (5D Heart) for the display of key diagnostic elements in basic sections.

Authors: Wan-Yu Hu, Jin-Hong Zhou, Xiao-Ying Tao, Shi-Yan Li, Bei Wang and Bo-Wen Zhao

The independent indicators for differentiating renal cell carcinoma from renal angiomyolipoma by contrast-enhanced ultrasound

The value of contrast-enhanced ultrasound (CEUS) in differentiating between renal cell carcinoma (RCC) and angiomyolipoma (AML) was analyzed. The purpose of this study was to identify the independent indicator...

Authors: Hongli Cao, Liang Fang, Lin Chen, Jia Zhan, Xuehong Diao, Yingchun Liu, Chen Lu, Zhengwang Zhang and Yue Chen

The application and accuracy of feature matching on automated cephalometric superimposition

The aim of this study was to establish a computer-aided automated method for cephalometric superimposition and to evaluate the accuracy of this method based on free-hand tracing.

Authors: Yiran Jiang, Guangying Song, Xiaonan Yu, Yuanbo Dou, Qingfeng Li, Siqi Liu, Bing Han and Tianmin Xu

Percentage fat fraction in magnetic resonance imaging: upgrading the osteoporosis-detecting parameter

Osteoporosis (OP) is a systemic metabolic bone disorder identified as an essential health issue worldwide. Orthopedic imaging approaches were commonly used with some limitations. Thus, our study aimed to inves...

Authors: Rong Chang, Xiaowen Ma, Yonghong Jiang, Dageng Huang, Xiujin Chen, Ming Zhang and Dingjun Hao

Automatic quantification of left ventricular function by medical students using ultrasound

Automatic analyses of echocardiograms may support inexperienced users in quantifying left ventricular (LV) function. We have developed an algorithm for fully automatic measurements of mitral annular plane syst...

Authors: Jahn Frederik Grue, Sigurd Storve, Håvard Dalen, Ole Christian Mjølstad, Stein O. Samstad, Torfinn Eriksen-Volnes, Hans Torp and Bjørn Olav Haugen

Cardiovascular magnetic resonance 4D flow analysis has a higher diagnostic yield than Doppler echocardiography for detecting increased pulmonary artery pressure

Pulmonary hypertension is definitively diagnosed by the measurement of mean pulmonary artery (PA) pressure (mPAP) using right heart catheterization. Cardiovascular magnetic resonance (CMR) four-dimensional (4D...

Authors: Joao G. Ramos, Alexander Fyrdahl, Björn Wieslander, Gert Reiter, Ursula Reiter, Ning Jin, Eva Maret, Maria Eriksson, Kenneth Caidahl, Peder Sörensson, Andreas Sigfridsson and Martin Ugander

False positive finding from malignancy-like lesions on FDG PET/CT: case report of tuberculosis patients

The F-18 fluorodeoxyglucose positron emission/computed tomography (FDG PET/CT) has become an established diagnostic imaging for malignancy. However, there are other diseases that can also be identified with FD...

Authors: Febby Hutomo, Ryan Yudistiro, Ivana Dewi Mulyanto and Hendra Budiawan

Comparison of ¹⁸F-sodium fluoride PET/CT, ¹⁸F-fluorocholine PET/CT and diffusion-weighted MRI for the detection of bone metastases in recurrent prostate cancer: a cost-effectiveness analysis in France

The diagnostic performance of ¹⁸F-sodium fluoride positron emission tomography/computed tomography (PET/CT) (NaF), ¹⁸F-fluorocholine PET/CT (FCH) and diffusion-weighted whole-body magnetic resonance imaging (DW-M...

Authors: Mathieu Gauthé, Kevin Zarca, Cyrielle Aveline, Frédéric Lecouvet, Sona Balogova, Olivier Cussenot, Jean-Noël Talbot and Isabelle Durand-Zaleski

Radiological evaluation in patients with clinical suspicion of cerebral venous sinus thrombosis presenting with nontraumatic headache - a retrospective observational study with a validation cohort

Clinical suspicion of cerebral venous sinus thrombosis (CVST) is imprecise due to non-specific symptoms such as headache. The aim was to retrospectively assess the diagnostic value of nonenhanced CT (neCT) in ...

Authors: Håkan Almqvist, Michael Mazya, Alberto Falk Delgado and Anna Falk Delgado

The impact of 18F-FDOPA-PET/MRI image fusion in detecting liver metastasis in patients with neuroendocrine tumors of the gastrointestinal tract

This study assesses the value of image fusion using 18F-fluoro-L-DOPA (18F-DOPA) positron emission tomography (PET) and magnetic resonance imaging (MRI) for examining patients with neuroendocrine tumors (NETs)...

Authors: O. Barachini, R. Bernt, S. Mirzaei, C. Pirich, K. Hergan and S. Zandieh

BSCN: bidirectional symmetric cascade network for retinal vessel segmentation

Retinal blood vessel segmentation has an important guiding significance for the analysis and diagnosis of cardiovascular diseases such as hypertension and diabetes. But the traditional manual method of retinal...

Authors: Yanfei Guo and Yanjun Peng

Adnexal torsion in the third trimester of pregnancy: a case report and diagnostic value of MR imaging

The torsion of normal adnexa is rare during pregnancy, especially in the third trimester. Nonspecific symptoms and signs as well as the limitations of ultrasound (US) make the diagnosis difficult, resulting in...

Authors: Wei Bai, Xiao Xu, Haizhu Xie, Chunjuan Sun, Kaili Che, Meijie Liu, Jing Liu, Yinghong Shi and Heng Ma

A post-market, multi-vessel evaluation of the imaging of peripheral arteries for diagnostic purposeS comparing optical Coherence tomogrApy and iNtravascular ultrasound imaging (SCAN)

Intravascular imaging plays an important part in diagnosis of vascular conditions and providing insight for treatment strategy. Two main imaging modalities are intravascular ultrasound (IVUS) and optical coher...

Authors: Edward Pavillard and Luke Sewall

Brain SegNet: 3D local refinement network for brain lesion segmentation

MR images (MRIs) accurate segmentation of brain lesions is important for improving cancer diagnosis, surgical planning, and prediction of outcome. However, manual and accurate segmentation of brain lesions fro...

Authors: Xiaojun Hu, Weijian Luo, Jiliang Hu, Sheng Guo, Weilin Huang, Matthew R. Scott, Roland Wiest, Michael Dahlweid and Mauricio Reyes

Accuracy of real-time shear wave elastography in staging hepatic fibrosis: a meta-analysis

Chronic liver disease (CLD) is an important cause of morbidity and mortality and can lead to hepatic fibrosis. This study was conducted to evaluate the diagnostic value of real-time shear wave elastography (SW...

Authors: Juan Fu, Biao Wu, Huazhi Wu, Feng Lin and Wei Deng

A strategy to account for noise in the X-variable to reduce underestimation in Logan graphical analysis for quantifying receptor density in positron emission tomography

The Logan graphical analysis (LGA) algorithm is widely used to quantify receptor density for parametric imaging in positron emission tomography (PET). Estimating receptor density, in terms of the non-displacea...

Authors: Paulus K. Shigwedha, Takahiro Yamada, Kohei Hanaoka, Kazunari Ishii, Yuichi Kimura and Yutaka Fukuoka

Can the low and high b-value distribution influence the pseudodiffusion parameter derived from IVIM DWI in normal brain?

Our study aims to reveal whether the low b-values distribution, high b-values upper limit, and the number of excitation (NEX) influence the accuracy of the intravoxel incoherent motion (IVIM) parameter derived...

Authors: Yu-Chuan Hu, Lin-Feng Yan, Yu Han, Shi-Jun Duan, Qian Sun, Gang-Feng Li, Wen Wang, Xiao-Cheng Wei, Dan-Dan Zheng and Guang-Bin Cui

Computed tomography evaluation of extensive intravenous angioleiomyoma: a case report

Uterine angioleiomyoma is a rare variant of leiomyoma, and the main therapy is complete surgery. This study introduces the benefit of three-dimensional computed tomography reconstruction for preoperative prepa...

Authors: Rui Sun, Hongwei Guan, Hui Li, Yixuan Bai, Fei Wang and Changzhong Li

Discrimination of mediastinal metastatic lymph nodes in NSCLC based on radiomic features in different phases of CT imaging

We aimed to develop radiomic models based on different phases of computed tomography (CT) imaging and to investigate the efficacy of models for diagnosing mediastinal metastatic lymph nodes (LNs) in non-small ...

Authors: Xue Sha, Guanzhong Gong, Qingtao Qiu, Jinghao Duan, Dengwang Li and Yong Yin

CNN-based survival model for pancreatic ductal adenocarcinoma in medical imaging

Cox proportional hazard model (CPH) is commonly used in clinical research for survival analysis. In quantitative medical imaging (radiomics) studies, CPH plays an important role in feature reduction and modeli...

Authors: Yucheng Zhang, Edrise M. Lobo-Mueller, Paul Karanicolas, Steven Gallinger, Masoom A. Haider and Farzad Khalvati

Iodine concentration and content measured by dual-source computed tomography are correlated to thyroid hormone levels in euthyroid patients: a cross-sectional study in China

The aim of this study was to investigate the correlation of the dual energy CT measured iodine concentration and total iodine content with blood measured thyroid parameters.

Authors: Zheng-Teng Li, Rui Zhai, Hong-Mei Liu, Min Wang and Dong-Mei Pan

Patient-adapted organ absorbed dose and effective dose estimates in pediatric 18F-FDG positron emission tomography/computed tomography studies

Organ absorbed doses and effective doses can be used to compare radiation exposure among medical imaging procedures, compare alternative imaging options, and guide dose optimization efforts. Individual dose es...

Authors: Brian M. Quinn, Yiming Gao, Usman Mahmood, Neeta Pandit-Taskar, Gerald Behr, Pat Zanzonico and Lawrence T. Dauer

Quantitative comparison of two-dimensional and three-dimensional strain measurement using MRI feature tracking in repair Fontan patients and normal child volunteers

The accuracy of 2D and 3D strain analyses was evaluated by comparing strain and cardiac function parameters in Fontan repair patients and normal child volunteers.

Authors: Liwei Hu, Qian Wang, Barton P. Gregory, Rong Zhen Ouyang, Aimin Sun, Chen Guo, Tongtong Han and Yumin Zhong

¹⁸F- FDG PET/CT-derived parameters predict clinical stage and prognosis of esophageal cancer

Although ¹⁸F- FDG PET/CT is validated in baseline workup of esophageal cancer to detect distant metastases, it remains underused in assessing local staging and biology of the primary tumor. This study aimed to ev...

Authors: Styliani Mantziari, Anastasia Pomoni, John O. Prior, Michael Winiker, Pierre Allemann, Nicolas Demartines and Markus Schäfer

Methadone-induced encephalopathy: a case series and literature review

Accidental ingestion or consumption of supra-therapeutic doses of methadone can result in neurological sequelae in humans. We aimed to determine the neurological deficits of methadone-poisoned patients admitte...

Authors: Maryam Haghighi-Morad, Zahra Naseri, Nazila Jamshidi, Hossein Hassanian-Moghaddam, Nasim Zamani and Leila Ahmad-Molaei

Dual-energy spectral CT quantitative parameters for the differentiation of Glioma recurrence from treatment-related changes: a preliminary study

Differentiating glioma recurrence from treatment-related changes can be challenging on conventional imaging. We evaluated the efficacy of quantitative parameters measured by dual-energy spectral computed tomog...

Authors: Yanchun Lv, Jian Zhou, Xiaofei Lv, Li Tian, Haoqiang He, Zhigang Liu, Yi Wu, Lujun Han, Meili Sun, Yadi Yang, Chengcheng Guo, Cong Li, Rong Zhang, Chuanmiao Xie, Yinsheng Chen and Zhongping Chen

Preliminary application of 3.0 T magnetic resonance chemical exchange saturation transfer imaging in brain metastasis of lung cancer

Lung cancer brain metastases are very common and one of the common causes of treatment failure. We aimed to examine the clinical use of chemical exchange saturation transfer (CEST) technology in the evaluation...

Authors: Yonggui Yang, Xiaobo Qu, Yihui Huang, Khan Afsar, Gen Yan, Gang Guo and Shaoyin Duan

Assessing and reducing PET radiotracer infiltration rates: a single center experience in injection quality monitoring methods and quality improvement

Successful injection of radiolabeled compounds is critical for positron emission tomography (PET) imaging. A poor quality injection limits the tracer availability in the body and can impact diagnostic results....

Authors: Dustin R. Osborne, Shelley N. Acuff, Michael Fang, Melissa D. Weaver and Yitong Fu

An enhanced adaptive non-local means algorithm for Rician noise reduction in magnetic resonance brain images

The Rician noise formed in magnetic resonance (MR) imaging greatly reduced the accuracy and reliability of subsequent analysis, and most of the existing denoising methods are suitable for Gaussian noise rather...

Authors: Kaixin Chen, Xiao Lin, Xing Hu, Jiayao Wang, Han Zhong and Linhua Jiang

Pre-contrast T1 and cartilage thickness as confounding factors in dGEMRIC when evaluating human cartilage adaptation to physical activity

The dGEMRIC (delayed Gadolinium-Enhanced MRI of Cartilage) technique has been used in numerous studies for quantitative in vivo evaluation of the relative glycosaminoglycan (GAG) content in cartilage. The purp...

Authors: Carl Johan Tiderius, Zana K. Hawezi, Lars E. Olsson and Leif E. Dahlberg

Automated classification of dense calcium tissues in gray-scale intravascular ultrasound images using a deep belief network

IVUS is widely used to quantitatively assess coronary artery disease. The purpose of this study was to automatically characterize dense calcium (DC) tissue in the gray scale intravascular ultrasound (IVUS) ima...

Authors: Juhwan Lee, Yoo Na Hwang, Ga Young Kim, Ji Yean Kwon and Sung Min Kim

Feasibility evaluation of micro-optical coherence tomography (μOCT) for rapid brain tumor type and grade discriminations: μOCT images versus pathology

Precise identification, discrimination and assessment of central nervous system (CNS) tumors is of critical importance to brain neoplasm treatment. Due to the complexity and limited resolutions of the existing...

Authors: Xiaojun Yu, Chi Hu, Wenfei Zhang, Jie Zhou, Qianshan Ding, M. T. Sadiq, Zeming Fan, Zhaohui Yuan and Linbo Liu

Reduced regional flow in the left ventricle after anterior acute myocardial infarction: a case control study using 4D flow MRI

Acute myocardial infarction (AMI) alters left ventricular (LV) hemodynamics, resulting in decreased global LV ejection fraction and global LV kinetic energy. We hypothesize that anterior AMI effects localized ...

Authors: Philip A. Corrado, Jacob A. Macdonald, Christopher J. François, Niti R. Aggarwal, Jonathan W. Weinsaft and Oliver Wieben

Comparative evaluation of image registration methods with different interest regions in lung cancer radiotherapy

Lung cancer is a leading cause of morbidity and mortality worldwide. Radiotherapy for lung cancer is beneficial in both the radical and palliative settings, and technologic advances in recent years now afford ...

Authors: Xiaohui Cao, Ming Liu, Fushan Zhai, Nan Li, Feng Li, Chaoen Bao, Yinliang Liu and Gang Chen

Association between basilar artery configuration and Vessel Wall features: a prospective high-resolution magnetic resonance imaging study

The relationship between intracranial vessel configuration and wall features remains poorly investigated. Therefore, we aimed to investigate the relationship between the distal and proximal anatomical configur...

Authors: Ziqi Xu, Mingyao Li, Zhikai Hou, Jinhao Lyu, Na Zhang, Xin Lou, Zhongrong Miao and Ning Ma

Time-lapse angiography of the ocular fundus: a new video-angiography

Ocular fundus angiography is an indispensable component of the tests utilized for fundus diseases. Dynamic angiography results can provide additional information; however, many difficulties remain. In this stu...

Authors: Chufeng Gu, Jili Chen, Tong Su and Qinghua Qiu

Diagnostic accuracy of multi-slice computed tomography in children with Abernethy malformation

Abernethy malformation is a rare congenital abnormality. Imaging examination is an important method for the diagnosis. The purpose of this study was to demonstrate manifestations of multi-slice computed tomogr...

Authors: Chen Guo, Yu-Min Zhong, Qian Wang, Li-Wei Hu, Xiao-Hong Gu, Hong Shao, Wei Wu, Jian-Feng Cao and Hai-Sheng Qiu

Evaluation of venous pathology of the lower extremities with triggered angiography non-contrast-enhanced magnetic resonance imaging

To explore the diagnostic performance of triggered angiography non-contrast-enhanced magnetic resonance imaging (TRANCE-MRI) for the evaluation of venous pathology of the lower extremity.

Authors: Yao-Kuang Huang, Yuan-Hsi Tseng, Chih-Hung Lin, Yuan-Hsiung Tsai, Yin-Chen Hsu, Shih-Chung Wang and Chien-Wei Chen

Inter and intra-reliability of ultrasonography for the measurement of abdominal subcutaneous & visceral adipose tissue thickness at 12 weeks gestation

Excess abdominal adiposity cause metabolic disturbances, particularly in pregnancy. Methods of accurate measurement are limited in pregnancy due to risks associated with these procedures. This study outlines a...

Authors: Alexandra Cremona, Kevin Hayes, Clodagh S. O’Gorman, Ciara Ní Laighin, Khadijah I. Ismail, Alan E. Donnelly, Jill Hamilton and Amanda Cotter

Magnetic resonance imaging findings of idiopathic granulomatous mastitis: can it be an indirect sign of treatment success or fail?

Authors: Ayşegül Altunkeser, Fatma Zeynep Arslan and Mehmet Ali Eryılmaz

Ultrasound assessment of tensile stress in carotid arteries of healthy human subjects with varying age

Arterial remodeling is thought to reflect the adaptation of the vessel wall to mechanical and hemodynamic stimuli and contributes to the progression of cardiovascular and cerebrovascular diseases. Tensile stre...

Authors: Xianghong Luo, Lianfang Du and Zhaojun Li

Evaluation of microvascular changes in the perifoveal vascular network using optical coherence tomography angiography (OCTA) in type I diabetes mellitus: a large scale prospective trial

Diabetic retinopathy (DR) is the leading cause of blindness in type 1 Diabetes Mellitus (DM) patients, as a consequence of impaired blood flow in the retina. Optical coherence tomography angiography (OCTA) is ...

Authors: Javier Zarranz-Ventura, Marina Barraso, Anibal Alé-Chilet, Teresa Hernandez, Cristian Oliva, Jesus Gascón, Anna Sala-Puigdollers, Marc Figueras-Roca, Irene Vinagre, Emilio Ortega, Enric Esmatjes and Alfredo Adan