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Neuroimaging

This section aims to publish articles related to the development, evaluation, and use of imaging techniques and image processing tools to image the nervous system. 

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  1. Neonatal hyperbilirubinemia is a common clinical condition that requires medical attention in newborns, which may develop into acute bilirubin encephalopathy with a significant risk of long-term neurological d...

    Authors: Miao Wu, Xiaoxia Shen, Can Lai, Weihao Zheng, Yingqun Li, Zhongli Shangguan, Chuanbo Yan, Tingting Liu and Dan Wu

    Citation: BMC Medical Imaging 2021 21:103

    Content type: Research article

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  2. Mobile 3-dimensional fluoroscopes are an integral part of modern neurosurgical operating theatres and can also be used in combination with free available image post processing to depict cerebral vessels. In pr...

    Authors: Thomas Linsenmann, Andrea Cattaneo, Alexander März, Judith Weiland, Christian Stetter, Robert Nickl and Thomas Westermaier

    Citation: BMC Medical Imaging 2021 21:94

    Content type: Research article

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  3. Differential diagnosis of tumour recurrence (TuR) from treatment effects (TrE), mostly induced by radiotherapy and chemotherapy, is still difficult by using conventional computed tomography (CT) or magnetic re...

    Authors: Cong Li, Chang Yi, Yingshen Chen, Shaoyan Xi, Chengcheng Guo, Qunying Yang, Jian Wang, Ke Sai, Ji Zhang, Chao Ke, Fanfan Chen, Yanchun Lv, Xiangsong Zhang and Zhongping Chen

    Citation: BMC Medical Imaging 2021 21:92

    Content type: Research article

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  4. The EU gadolinium-based contrast agents (GBCA) market has changed in recent years due to the European Medicines Agency decision to suspend the marketing authorisation of linear GBCA and the marketing authorisa...

    Authors: Jarl Åsbjørn Jakobsen, Carlo Cosimo Quattrocchi, Frank H. H. Müller, Olivier Outteryck, Andrés Alcázar, Wolfgang Reith, Patricia Fraga, Valeria Panebianco, Alexis Sampedro and Radoslaw Pietura

    Citation: BMC Medical Imaging 2021 21:74

    Content type: Research article

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  5. Brain metastases are particularly common in patients with small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), with NSCLC showing a less  aggressive clinical course and lower chemo- and radio ...

    Authors: Sebastian Johannes Müller, Eya Khadhraoui, Nicole E. Neef, Christian Heiner Riedel and Marielle Ernst

    Citation: BMC Medical Imaging 2021 21:70

    Content type: Research article

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  6. Intravenous thrombolysis (IVT) is a rapid and effective treatment in the early stage of ischemic stroke patients and the purpose of this work is to explore the significance of Hounsfield unit (HU) value in Alb...

    Authors: Zhengqi Zhu, Ru Zhang, Kaixuan Ren, Ruochen Cong, Xiangyang Zhu, Li Zhu and Tianle Wang

    Citation: BMC Medical Imaging 2021 21:62

    Content type: Research article

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  7. Adult-attention-deficit-hyperactive-disorder (ADHD) is often unrecognized condition. FMRI examination along with neuropsychological testing might strengthen the diagnosis. We hypothesized that ADHD-adults with...

    Authors: Jatta Berberat, Ruth Huggenberger, Margherita Montali, Philipp Gruber, Achmed Pircher, Karl-Olof Lövblad, Hanspeter E. Killer and Luca Remonda

    Citation: BMC Medical Imaging 2021 21:53

    Content type: Research article

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  8. The visualization of the tibial nerve and its branches in the ankle canal is helpful for the diagnosis of local lesions and compression, and it is also useful for clinical observation and surgical planning. Th...

    Authors: Yan Zhang, Xucheng He, Juan Li, Ju Ye, Wenjuan Han, Shanshan Zhou, Jianzhong Zhu, Guisheng Wang and Xiaoxia Chen

    Citation: BMC Medical Imaging 2021 21:51

    Content type: Research article

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  9. This study aims to compare the difference of the brain changes of glucose metabolism between temporal lobe epilepsy patients (TLE) with major depressive disorder and temporal TLE without major depressive disor...

    Authors: Jin-Feng Wen, Xin-Wen Guo, Xiang-Yi Cao, Ji-Wu Liao, Ping Ma, Xiang-Shu Hu and Ji-Yang Pan

    Citation: BMC Medical Imaging 2021 21:33

    Content type: Research article

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  10. Primary lymphoma of the cavernous sinus is a rare form of extranodal non-Hodgkin lymphoma, of which very few cases have been reported in the published literature. This report presents the MRI findings with app...

    Authors: Cheng-Chun Yang, Tai-Yuan Chen, Yu-Kun Tsui and Ching-Chung Ko

    Citation: BMC Medical Imaging 2021 21:25

    Content type: Case report

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  11. Based on conventional MRI images, it is difficult to differentiatepseudoprogression from true progressionin GBM patients after standard treatment, which isa critical issue associated with survival. The aim of ...

    Authors: Ying-Zhi Sun, Lin-Feng Yan, Yu Han, Hai-Yan Nan, Gang Xiao, Qiang Tian, Wen-Hui Pu, Ze-Yang Li, Xiao-Cheng Wei, Wen Wang and Guang-Bin Cui

    Citation: BMC Medical Imaging 2021 21:17

    Content type: Research article

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  12. To investigate the effect of using a Rician nonlocal means (NLM) filter on quantification of diffusion tensor (DT)- and diffusion kurtosis (DK)-derived metrics in various anatomical regions of the human brain ...

    Authors: Zhongping Zhang, Dhanashree Vernekar, Wenshu Qian and Mina Kim

    Citation: BMC Medical Imaging 2021 21:16

    Content type: Research article

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  13. Ultra-high field magnetic resonance imaging (MR) may be used to improve intracranial blood flow measurements. However, standard cardiac synchronization methods tend to fail at ultra-high field MR. Therefore, t...

    Authors: Karin Markenroth Bloch, Fabian Kording and Johannes Töger

    Citation: BMC Medical Imaging 2020 20:128

    Content type: Technical advance

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  14. This study aims to compare proton density weighted magnetic resonance imaging (MRI) zero echo time (ZTE) and head atlas attenuation correction (AC) to the reference standard computed tomography (CT) based AC for

    Authors: Francesca De Luca, Martin Bolin, Lennart Blomqvist, Cecilia Wassberg, Heather Martin and Anna Falk Delgado

    Citation: BMC Medical Imaging 2020 20:126

    Content type: Research article

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  15. Reported date of last menstrual period and ultrasonography measurements are the most commonly used methods for determining gestational age in antenatal life. However, the mother cannot always determine the las...

    Authors: Yuequan Shi, Yunjing Xue, Chunxia Chen, Kaiwu Lin and Zuofu Zhou

    Citation: BMC Medical Imaging 2020 20:125

    Content type: Research article

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  16. To compare the diagnostic performance of neurite orientation dispersion and density imaging (NODDI), mean apparent propagator magnetic resonance imaging (MAP-MRI), diffusion kurtosis imaging (DKI), diffusion t...

    Authors: Jiaji Mao, Weike Zeng, Qinyuan Zhang, Zehong Yang, Xu Yan, Huiting Zhang, Mengzhu Wang, Guang Yang, Minxiong Zhou and Jun Shen

    Citation: BMC Medical Imaging 2020 20:124

    Content type: Research article

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  17. The revised 2016 WHO-Classification of CNS-tumours now integrates molecular information of glial brain tumours for accurate diagnosis as well as for the development of targeted therapies. In this prospective s...

    Authors: Pamela Franco, Urs Würtemberger, Karam Dacca, Irene Hübschle, Jürgen Beck, Oliver Schnell, Irina Mader, Harald Binder, Horst Urbach and Dieter Henrik Heiland

    Citation: BMC Medical Imaging 2020 20:123

    Content type: Study protocol

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  18. Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by loss of upper and lower motor neurons. There is a need for an imaging biomarker to track disease progression. Previously, mag...

    Authors: Ashwag R. Alruwaili, Kerstin Pannek, Robert D. Henderson, Marcus Gray, Nyoman D. Kurniawan and Pamela A. McCombe

    Citation: BMC Medical Imaging 2020 20:90

    Content type: Research article

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  19. This paper addresses issues of brain tumor, glioma, classification from four modalities of Magnetic Resonance Image (MRI) scans (i.e., T1 weighted MRI, T1 weighted MRI with contrast-enhanced, T2 weighted MRI a...

    Authors: Chenjie Ge, Irene Yu-Hua Gu, Asgeir Store Jakola and Jie Yang

    Citation: BMC Medical Imaging 2020 20:87

    Content type: Technical advance

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  20. 18F-THK5351 was recently shown to bind to monoamine oxidase B (MAO-B) with high affinity. MAO-B is highly concentrated in astrocytes and increases during astrogliosis. Therefore, 18F-THK5351 accumulates in lesion...

    Authors: Kenji Ishibashi, Yoshiharu Miura, Kosei Hirata, Jun Toyohara and Kenji Ishii

    Citation: BMC Medical Imaging 2020 20:81

    Content type: Case report

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  21. Accurate identification of Parkinson’s disease (PD) and Parkinsonism-Plus syndrome (PPS), especially in the early stage of the disease, is very important. The purpose of this study was to investigate the discr...

    Authors: Lina Cheng, Xiaoyan Wu, Ruomi Guo, Yuzhou Wang, Wensheng Wang, Peng He, Hanbo Lin and Jun Shen

    Citation: BMC Medical Imaging 2020 20:78

    Content type: Research article

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  22. This study aimed to investigate integrating radiomics with clinical factors in cranial computed tomography (CT) to predict ischemic strokes in patients with silent lacunar infarction (SLI).

    Authors: Jie-hua Su, Ling-wei Meng, Di Dong, Wen-yan Zhuo, Jian-ming Wang, Li-bin Liu, Yi Qin, Ye Tian, Jie Tian and Zhao-hui Li

    Citation: BMC Medical Imaging 2020 20:77

    Content type: Research article

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  23. Diffusion and perfusion MRI can invasively define physical properties and angiogenic features of tumors, and guide the individual treatment. The purpose of this study was to investigate whether the diffusion a...

    Authors: Zhen Xing, Nannan Kang, Yu Lin, Xiaofang Zhou, Zebin Xiao and Dairong Cao

    Citation: BMC Medical Imaging 2020 20:62

    Content type: Research article

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  24. To investigate the ability of amide proton transfer (APT) weighted magnetic resonance imaging (MRI), arterial spin labeling (ASL), diffusion weighted imaging (DWI) and the combination for differentiating high-...

    Authors: Xiao-wei Kang, Yi-bin Xi, Ting-ting Liu, Ning Wang, Yuan-qiang Zhu, Xing-rui Wang and Fan Guo

    Citation: BMC Medical Imaging 2020 20:50

    Content type: Research article

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  25. Hippocampal sclerosis (HS) is associated with post-surgery outcome in patients with temporal lobe epilepsy (TLE), and an automated method that quantifies HS severity is still lacking. Here, we aim to propose a...

    Authors: Wanchen Dou, Lei Zhao, Changbao Su, Qiang Lu, Qi Liu, Jinzhu Guo, Yuming Zhao, Yishan Luo, Lin Shi, Yiwei Zhang, Renzhi Wang and Feng Feng

    Citation: BMC Medical Imaging 2020 20:42

    Content type: Research article

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  26. Clinical suspicion of cerebral venous sinus thrombosis (CVST) is imprecise due to non-specific symptoms such as headache. The aim was to retrospectively assess the diagnostic value of nonenhanced CT (neCT) in ...

    Authors: Håkan Almqvist, Michael Mazya, Alberto Falk Delgado and Anna Falk Delgado

    Citation: BMC Medical Imaging 2020 20:24

    Content type: Research article

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  27. Our study aims to reveal whether the low b-values distribution, high b-values upper limit, and the number of excitation (NEX) influence the accuracy of the intravoxel incoherent motion (IVIM) parameter derived...

    Authors: Yu-Chuan Hu, Lin-Feng Yan, Yu Han, Shi-Jun Duan, Qian Sun, Gang-Feng Li, Wen Wang, Xiao-Cheng Wei, Dan-Dan Zheng and Guang-Bin Cui

    Citation: BMC Medical Imaging 2020 20:14

    Content type: Research article

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  28. Accidental ingestion or consumption of supra-therapeutic doses of methadone can result in neurological sequelae in humans. We aimed to determine the neurological deficits of methadone-poisoned patients admitte...

    Authors: Maryam Haghighi-Morad, Zahra Naseri, Nazila Jamshidi, Hossein Hassanian-Moghaddam, Nasim Zamani and Leila Ahmad-Molaei

    Citation: BMC Medical Imaging 2020 20:6

    Content type: Research article

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  29. Differentiating glioma recurrence from treatment-related changes can be challenging on conventional imaging. We evaluated the efficacy of quantitative parameters measured by dual-energy spectral computed tomog...

    Authors: Yanchun Lv, Jian Zhou, Xiaofei Lv, Li Tian, Haoqiang He, Zhigang Liu, Yi Wu, Lujun Han, Meili Sun, Yadi Yang, Chengcheng Guo, Cong Li, Rong Zhang, Chuanmiao Xie, Yinsheng Chen and Zhongping Chen

    Citation: BMC Medical Imaging 2020 20:5

    Content type: Research article

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  30. Precise identification, discrimination and assessment of central nervous system (CNS) tumors is of critical importance to brain neoplasm treatment. Due to the complexity and limited resolutions of the existing...

    Authors: Xiaojun Yu, Chi Hu, Wenfei Zhang, Jie Zhou, Qianshan Ding, M. T. Sadiq, Zeming Fan, Zhaohui Yuan and Linbo Liu

    Citation: BMC Medical Imaging 2019 19:102

    Content type: Research article

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  31. The relationship between intracranial vessel configuration and wall features remains poorly investigated. Therefore, we aimed to investigate the relationship between the distal and proximal anatomical configur...

    Authors: Ziqi Xu, Mingyao Li, Zhikai Hou, Jinhao Lyu, Na Zhang, Xin Lou, Zhongrong Miao and Ning Ma

    Citation: BMC Medical Imaging 2019 19:99

    Content type: Research article

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  32. Primary angiitis of the central nervous system (PACNS) is a rare disease, and tumor-like primary angiitis of the central nervous system is even rarer. Histopathology is the gold standard for tumor-mimicking PA...

    Authors: Yu-Jing Huang, Li Zhang, Ying Mao and Guang-Xian Nan

    Citation: BMC Medical Imaging 2019 19:79

    Content type: Case report

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  33. Flat detector CT – angiography (FDCTA) has become a valuable imaging tool in post- and peri-interventional imaging after neurovascular procedures. Metal artifacts produced by radiopaque implants like clips or ...

    Authors: Nadine Amelung, Volker Maus, Daniel Behme, Ismini E. Papageorgiou, Johanna Rosemarie Leyhe, Michael Knauth and Marios Nikos Psychogios

    Citation: BMC Medical Imaging 2019 19:66

    Content type: Research article

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  34. Accurate segmentation of brain tumors is vital for the gross tumor volume (GTV) definition in radiotherapy. Functional MR images like apparent diffusion constant (ADC) and fractional anisotropy (FA) images can...

    Authors: Ranran Sun, Keqiang Wang, Lu Guo, Chengwen Yang, Jie Chen, Yalin Ti and Yu Sa

    Citation: BMC Medical Imaging 2019 19:48

    Content type: Research article

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  35. Diagnosis of giant cell arteritis by temporal artery biopsy is time-consuming and visual loss lies in the first week after its diagnosis. The purpose of the study was to test the hypothesis that ultrasound can...

    Authors: Quan Zou, Sumei Ma and Xinghu Zhou

    Citation: BMC Medical Imaging 2019 19:47

    Content type: Research article

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  36. Posterior reversible encephalopathy syndrome (PRES) is a rare clinic-radiological entity characterized by headache, an altered mental status, visual disturbances, and seizures. Reversible splenial lesion syndr...

    Authors: Qing Yang, Can-can Chang, Mengxiao Liu and Yong-qiang Yu

    Citation: BMC Medical Imaging 2019 19:35

    Content type: Case report

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  37. Initial reports of 23Na magnetic resonance imaging (MRI) date back to the 1970s. However, methodological challenges of the technique hampered its widespread adoption for many years. Recent technical developments ...

    Authors: Melissa M. Meyer, Stefan Haneder, Simon Konstandin, Johannes Budjan, John N. Morelli, Lothar R. Schad, Hans U. Kerl, Stefan O. Schoenberg and Christoph Kabbasch

    Citation: BMC Medical Imaging 2019 19:26

    Content type: Research article

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  38. The imaging findings of hypoglycemic encephalopathy can be considerably similar to those of ischemic infarction or toxic leukoencephalopathy. We demonstrated unusual magnetic resonance (MR) imaging features of...

    Authors: Kai-I Chuang, Kevin Li-Chun Hsieh and Cheng-Yu Chen

    Citation: BMC Medical Imaging 2019 19:11

    Content type: Case report

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  39. The purpose of this retrospective review is to determine the MR imaging features of pilocytic astrocytoma (PA) in the spinal cord to help neuroradiologists preoperatively differentiate PA from other intramedul...

    Authors: De-jun She, Yi-ping Lu, Ji Xiong, Dao-ying Geng and Bo Yin

    Citation: BMC Medical Imaging 2019 19:5

    Content type: Research article

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  40. To compare the Self-referenced and Referenced measurement methods in assessing basilar artery (BA) atherosclerotic plaque employing dark blood high-resolution MRI at 3 Tesla.

    Authors: Luguang Chen, Qian Zhan, Wenjia Peng, Tao Song, Qi Liu and Jianping Lu

    Citation: BMC Medical Imaging 2018 18:49

    Content type: Research article

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  41. Micro-CT holds promising potential for phenotyping and histological purposes. However, few have clarified the difference in the neuroimaging quality between ex vivo and in vivo micro-CT scanners. In addition, ...

    Authors: Ko-Chin Chen, Alon Arad, Zan-Ming Song and David Croaker

    Citation: BMC Medical Imaging 2018 18:38

    Content type: Research article

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  42. As a common clinical symptom that often bothers midlife females, migraine is closely associated with perimenopause. Previous studies suggest that one of the most prominent triggers is the sudden decline of est...

    Authors: Bo Hu, Xu Wang, Jie-bing He, Yu-jie Dai, Jin Zhang, Ying Yu, Qian Sun, Lin-FengYan, Yu-Chuan Hu, Hai-Yan Nan, Yang Yang, Alan D. Kaye, Guang-Bin Cui and Wen Wang

    Citation: BMC Medical Imaging 2018 18:26

    Content type: Study protocol

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  43. In a prospective cohort of patients with transient ischemic attack (TIA), we investigated usefulness and feasibility of arterial spin labeling (ASL) perfusion and susceptibility weighted imaging (SWI) alone an...

    Authors: Inger Havsteen, Lasse Willer, Christian Ovesen, Janus Damm Nybing, Karen Ægidius, Jacob Marstrand, Per Meden, Sverre Rosenbaum, Marie Norsker Folke, Hanne Christensen and Anders Christensen

    Citation: BMC Medical Imaging 2018 18:24

    Content type: Research article

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