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Table 1 Univariate analysis of clinical characteristics and ultrasound features of lymph nodes in the MTC and PTC groups

From: Ultrasonographic features of cervical lymph node metastases from medullary thyroid cancer: a retrospective study

 

MTC (n, %)

PTC (n, %)

P value

No. of LNs

52

234

 

No. of patients

42

222

 

Clinical characteristics

Gender

   

 Male

17 (40.48)

60 (27.03)

0.079

 Female

25 (59.52)

162 (72.97)

 

Age

46.81 ± 13.05

39.09 ± 12.05

< 0.001 (Z = − 3.854)

Location

   

 Lateral

34 (65.38)

179 (76.50)

0.096

 Central

18 (34.62)

55 (23.50)

 

Ultrasound features

Long-axis diameter

16.43 ± 10.36

12.32 ± 6.93

0.001

 > 8.95

45 (86.54)

148 (60.91)

0.004#

 < 8.95

7 (13.46)

86 (39.09)

 

Short-axis diameter

8.53 ± 5.79

5.86 ± 2.61

< 0.001

 > 7.85

24 (46.15)

43 (18.38)

< 0.001#

 < 7.85

28 (53.85)

191 (81.62)

 

L/S

   

 ≤ 2

30 (57.69)

133 (56.84)

0.910

 > 2

22 (42.31)

101 (43.16)

 

Shape

   

 Irregular

3 (5.77)

5 (2.11)

0.150*

 Regular

47 (94.23)

229 (97.89)

 

Border

   

 Unsharp

2 (3.85)

4 (2.14)

0.300*

 Sharp

50 (96.15)

230 (97.86)

 

Hilum

   

 Absent

47 (90.38)

167 (71.37)

0.004#

 Present

5 (9.62)

67 (28.63)

 

Echogenicity

   

 Hyperechoic

19 (36.54)

67 (28.63)

0.261

 Isoechoic or hypoechoic

33 (63.46)

167(71.37)

 

Calcifications

   

 Present

11 (21.15)

139 (59.40)

 < 0.001#

 Absent

41 (78.85)

95 (40.60)

 

Cystic change

   

 Present

2 (3.85)

29 (12.39)

0.085*

 Absent

50 (96.15)

205 (87.61)

 

Vascularity pattern

   

 Abnormal flow

31 (59.61)

101 (43.16)

0.031#

 Hilar flow or absent flow

21 (40.38)

133 (56.84)

 
  1. *using Fisher's exact tests, others using chi-square (χ2); #enrolled into Multivariate Logistic Regression