Variables | AUC | 95%CI | Sensitivity (%) | Specificity (%) | Cut-off value | Y-index | P | |
---|---|---|---|---|---|---|---|---|
PH | 4 weeks | 0.78 | (0.62, 0.94) | 80.00 | 80.00 | ≥ 865.00 | 0.60 | 0.010 |
6 weeks | 0.74 | (0.58, 0.91) | 64.00 | 90.00 | ≥ 1402.00 | 0.54 | 0.026 | |
8 weeks | 0.75 | (0.57, 0.93) | 76.00 | 70.00 | ≥ 1476.50 | 0.46 | 0.024 | |
TTP | 4 weeks | 0.58 | (0.35, 0.81) | 88.00 | 40.00 | ≤ 32.50 | 0.28 | 0.454 |
6 weeks | 0.60 | (0.35, 0.85) | 84.00 | 50.00 | ≤ 36.00 | 0.34 | 0.342 | |
8 weeks | 0.59 | (0.35, 0.84) | 100.00 | 40.00 | ≤ 44.50 | 0.40 | 0.391 | |
MSI | 4 weeks | 0.78 | (0.58, 0.98) | 96.00 | 70.00 | ≥ 0.90 | 0.66 | 0.010 |
6 weeks | 0.77 | (0.58, 0.95) | 92.00 | 60.00 | ≥ 1.21 | 0.52 | 0.014 | |
8 weeks | 0.77 | (0.60, 0.95) | 76.00 | 80.00 | ≥ 1.72 | 0.56 | 0.013 | |
Emax | 4 weeks | 0.75 | (0.56, 0.94) | 68.00 | 80.00 | ≥ 1.07 | 0.48 | 0.021 |
6 weeks | 0.78 | (0.62, 0.94) | 56.00 | 100.00 | ≥ 1.66 | 0.56 | 0.012 | |
8 weeks | 0.83 | (0.68, 0.97) | 84.00 | 80.00 | ≥ 2.28 | 0.64 | 0.003 | |
SER | 4 weeks | 0.78 | (0.60, 0.97) | 60.00 | 90.00 | ≥ 1.01 | 0.50 | 0.010 |
6 weeks | 0.78 | (0.62, 0.94) | 84.00 | 70.00 | ≥ 1.22 | 0.54 | 0.011 | |
8 weeks | 0.88 | (0.76, 0.99) | 76.00 | 100.00 | ≥ 1.78 | 0.76 | 0.001 | |
Washout | 4 weeks | 0.46 | (0.20, 0.71) | 76.00 | 50.00 | ≥ 11.49 | 0.26 | 0.701 |
6 weeks | 0.42 | (0.20, 0.64) | 100.00 | 10.00 | ≥ 12.84 | 0.10 | 0.465 | |
8 weeks | 0.54 | (0.29, 0.79) | 88.00 | 50.00 | ≥ 25.25 | 0.38 | 0.715 |