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Table 3 Receiver operating characteristic (ROC) analysis of peak parameters and Washout in diagnosing early-phase spinal tuberculosis

From: Early diagnosis of spinal tuberculosis by magnetic resonance: perfusion weighted imaging in a rabbit model

Variables

AUC

95%CI

Sensitivity (%)

Specificity (%)

Cut-off value

Y-index

P

PH

4 weeks

0.78

(0.62, 0.94)

80.00

80.00

 ≥ 865.00

0.60

0.010

6 weeks

0.74

(0.58, 0.91)

64.00

90.00

 ≥ 1402.00

0.54

0.026

8 weeks

0.75

(0.57, 0.93)

76.00

70.00

 ≥ 1476.50

0.46

0.024

TTP

4 weeks

0.58

(0.35, 0.81)

88.00

40.00

 ≤ 32.50

0.28

0.454

6 weeks

0.60

(0.35, 0.85)

84.00

50.00

 ≤ 36.00

0.34

0.342

8 weeks

0.59

(0.35, 0.84)

100.00

40.00

 ≤ 44.50

0.40

0.391

MSI

4 weeks

0.78

(0.58, 0.98)

96.00

70.00

 ≥ 0.90

0.66

0.010

6 weeks

0.77

(0.58, 0.95)

92.00

60.00

 ≥ 1.21

0.52

0.014

8 weeks

0.77

(0.60, 0.95)

76.00

80.00

 ≥ 1.72

0.56

0.013

Emax

4 weeks

0.75

(0.56, 0.94)

68.00

80.00

 ≥ 1.07

0.48

0.021

6 weeks

0.78

(0.62, 0.94)

56.00

100.00

 ≥ 1.66

0.56

0.012

8 weeks

0.83

(0.68, 0.97)

84.00

80.00

 ≥ 2.28

0.64

0.003

SER

4 weeks

0.78

(0.60, 0.97)

60.00

90.00

 ≥ 1.01

0.50

0.010

6 weeks

0.78

(0.62, 0.94)

84.00

70.00

 ≥ 1.22

0.54

0.011

8 weeks

0.88

(0.76, 0.99)

76.00

100.00

 ≥ 1.78

0.76

0.001

Washout

4 weeks

0.46

(0.20, 0.71)

76.00

50.00

 ≥ 11.49

0.26

0.701

6 weeks

0.42

(0.20, 0.64)

100.00

10.00

 ≥ 12.84

0.10

0.465

8 weeks

0.54

(0.29, 0.79)

88.00

50.00

 ≥ 25.25

0.38

0.715

  1. AUC area under ROC curve, 95%CI 95% Confidence interval, PH peak height, TTP time to peak, MSI maximum slope of increase, Emax Maximum signal enhancement rate, SER Signal enhancement ratio