Whole-lesion apparent diffusion coefficient (ADC) histogram as a quantitative biomarker to preoperatively differentiate stage IA endometrial carcinoma from benign endometrial lesions

Table 1 MR imaging protocol

	Axial T1WI	Axial T2WI	Sagittal T2WI	Axial oblique T2WI	Axial DWI*	Axial T1WI postcontrast
GE signa excite HD 3.0T
Technique	FSE	FS FSE	FSE	FSE	SS-EPI	LAVA
TR (ms)/TE (ms)	620/8.2	5900/121	4920/139.1	4900/131.5	4400/64.3	4.1/1.8
Field of view (cm)	38.0	34.0	30.0	22.0	34.0	35.0
Matrix (phase × frequency)	320 × 224	320 × 256	320 × 256	320 × 256	256 × 256	350 × 350
Slice thickness (mm)	5	5	4	3	5	1
Slice gap	1	1	0.4	0	1	0
b value(s/mm²)	–	–	–	–	0, 800	–
GE Discovery HD750 3.0T
Technique	LAVA-Flex	FS FSE	FSE	FSE	SS-EPI	LAVA
TR (ms)/TE (ms)	4.2/1.3	5100/106.6	5620/135.6	5500/102.0	5500/62.7	7.9/4.1
Field of view (cm)	34.0	34.0	30.0	22.0	34.0	35.0
Matrix (phase × frequency)	320 × 224	320 × 256	320 × 256	320 × 256	128 × 128	350 × 350
Slice thickness (mm)	3	5	4	3	5	1
Slice gap	0	1	0.4	0	1	0
b value (s/mm²)	–	–	–	–	0, 800	–

T1WI, T1-weighted imaging; T2WI, T2-weighted imaging; FS, fat suppression; FSE, fast-recovery fast spin echo; DWI, diffusion-weighted imaging; SS-EPI, single-shot echo-planar imaging; LAVA-Flex, liver acquisition with volume acceleration-flexible; GRE, gradient echo; TR, repetition time; TE, echo time
*ADC maps were calculated voxel by voxel with the monoexponential model using formula: \({\text{ADC}} = {\text{ln}}\left( {S0/{\text{S}}800} \right)/\left( {b800 - b0} \right)\) where S800 and S0 are the signal intensities with and without a diffusion gradient, respectively

ISSN: 1471-2342