Combined model of radiomics, clinical, and imaging features for differentiating focal pneumonia-like lung cancer from pulmonary inflammatory lesions: an exploratory study

Table 1 Clinical and CT morphological features between the F-PLC and F-PIL groups

Characteristics	F-PLC group (n = 209)	F-PIL group (n = 137)	p-Value
Age (years)			< 0.001^a
Median ± interquartile range	64 ± 12	55 ± 16
Gender			< 0.001^b
Male	100 (47.85%)	93 (67.88%)
Female	109 (52.15%)	44 (32.12%)
Smoking history			0.024^b
Smokers	84 (40.19%)	72 (52.55%)
Non-smokers	125 (59.81%)	65 (47.45%)
Respiratory symptoms^d			< 0.001^b
With symptoms	126 (60.29%)	113 (82.48%)
Without symptoms	83 (39.71%)	24 (17.52%)
Lesion size (mm)			0.067^c
Mean ± standard deviation	43.17 ± 18.47	46.75 ± 16.57
Margin			0.302^b
Well-defined	138 (66.03%)	83 (60.58%)
Ill-defined	71 (33.97%)	54 (39.42%)
Spiculation	14 (6.70%)	9 (6.57%)	0.962^b
Air bronchogram	59 (28.23%)	19 (13.87%)	0.002^b
Necrosis	17 (8.13%)	61 (44.53%)	< 0.001^b
Calcification	13 (6.22%)	15 (10.95%)	0.115^b
Lymphadenopathy	66 (31.58%)	35 (25.55%)	0.227^b
Pleural attachment	103 (49.28%)	118 (86.13%)	< 0.001^b
Pleural effusion	13 (6.22%)	6 (4.38%)	0.462^b

CT computed tomography, F-PLC focal pneumonia-like lung cancer, F-PIL focal pulmonary inflammatory lesion
^aMann–Whitney U test
^bChi-square test
^cTwo-independent-samples Student’s t-test
^dRespiratory symptoms including fever, cough, sputum, blood in sputum, hemoptysis, and chest pain

ISSN: 1471-2342